The Korean Journal of Pharmacology (대한약리학회지)

The Korean Society of Pharmacology (대한약리학회)
권호 표지

The influence of Calcium, Magnesium, Sodium and Potassium Ion on the Adenosintriphosphatase activity of heart and skeletal microsomal fraction of rabbits.

가토심장(家兎心臟) 및 골격근(骨格筋)에서 분리(分離)한 Microsome 분획내(分劃內) ATPase 활성도(活性度)에 대(對)한 $Mg^{++}$, $Ca^{++}$, $Na^+$ 및 $K^+$의 영향(影響)

  • Choi, Sin-Jyoung (Department of Pharmacology, College of Medicine, Pusan National University) ;
  • Hong, Ki-Whan (Department of Pharmacology, College of Medicine, Pusan National University) ;
  • Kim, Gui-Tae (Department of Pharmacology, College of Medicine, Pusan National University)
  • 최신정 (부산대학교 의과대학 약리학교실) ;
  • 홍기환 (부산대학교 의과대학 약리학교실) ;
  • 김규태 (부산대학교 의과대학 약리학교실)
  • Published : 1966.05.01
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Abstract

The microsomal fraction is isolated from rabbit heart and skeletal muscle. The fraction is found to contain the $Na^+$-and $K^+$-activated ATPase. The maximal ATPase activity is obtained in $Na^+$ and $K^+$ concentration of 100 mM. Calcium itself stimulates the $Na^+$-and $K^+$-activated portion of ATPase in the presence of $Mg^{++}$. However, calcium does not stimulate ATPase in the absence of $Mg^{++}$.

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