The Effect of Crude Drug Preparation Containing Capricornidis Cornu on the Amount of Lipids in Serum from Rabbit

영양각(羚羊角)(Capricornidis Cornu)제제(製劑)가 가토혈청중(家兎血淸中) 지질함량(脂質含量) 변화(變化)에 미치는 영향(影響) (II)

  • Jung, Jee-Chang (Department of Pharmacology, School of Medicine Kyung Hee University) ;
  • Park, Tae-Gwan (Department of Pharmacology, School of Medicine Kyung Hee University) ;
  • Han, Dae-Sup (Department of Pharmacology, School of Medicine Kyung Hee University)
  • 정지창 (경희대학교 의과대학 약리학교실) ;
  • 박태권 (경희대학교 의과대학 약리학교실) ;
  • 한대섭 (경희대학교 의과대학 약리학교실)
  • Published : 1971.06.30

Abstract

The effect of Capricornidis Cornu (C.C) on the amount of total cholesterol, triglycerides, and phospholipid in serum from rabbit were observed. The preparations were extracted by methanol, and extracted samples were oraly adminstrated to the rabbits fasted for three days. After three days starvation, the amounts of total cholesterol and triglycerides in serum of the rabbit were markedly increased, while phospholipid was slightly decreased. The amount of total cholesterol and triglycerides were gradually decreased by adminstration of the extracted samples and were returned to the control leveles after 15 days. However, the amount of phospholipid was increased to higher than the control levels by adminstraion of the drug. According to the above results, it would be concluded that the extract of C.C. and crude drug preparation containing C.C. influences for the recovery of the increased amounts of total cholesterol and triglycerides by abnormal metabolism to the normal on rabbit.

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