Toxicological Research

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
권호 표지

STUDIES OF THIAMIN $(VATAMIN B_1)$ EFFECTS ON LEAD POISONING IN RATS

  • Kang, Jong-Koo (College of Veterinary Medicine, Seoul National University) ;
  • Lee, Joon-Sup (College of Veterinary Medicine, Seoul National University) ;
  • Lee, Yong-Soon (College of Veterinary Medicine, Seoul National University)
  • Published : 1985.12.01
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Abstract

The purpose of this study was to investigate whether or not $VATAMIN B_1$ (thiamin hydrochloride) could prevent and/or treat lead posoning in rats. Sprague-Dawley used in this experiment were divided into three group; control group compound group (thiamin 10mg+0.4% lead acetate solution) lead group (0.4% lead acetate solution). The results obtained were summarized as follow; 1. The body weight gain of treated groups (compound group and lead group) were lowered significantly in comparsion with those of control groups (p<0.01). But the significant difference between treated group was not observed (p<0.05).

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