Toxicological Research

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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신장근위곡세뇨관 소포를 이용한 신장독성 실험모델 개발 2.Uranyl acetate가 신장근위곡세뇨관 소포에서의 물질이동에 미치는 영향

  • 이영재 (서울대학교 수의과대학) ;
  • 이창업 (서울대학교 수의과대학) ;
  • 류판동 (서울대학교 수의과대학) ;
  • 박종명 (농총진흥청 가축위생연구소) ;
  • 박근식 (농총진흥청 가축위생연구소)
  • Published : 1992.06.01
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Abstract

Basolateral and brush border membrance (BLM and BBM) vesicles of renal proximal tubules were prepared from adult male New Zealand White rabbits to develop an experimental for assessment of nephrotoxicity. PAH uptakes using BLMV, and glucose and leucine uptakes using BBMV were measured in the rabbits treated uranyl acetate. In addition, urinalysis and histopathological studies were performed to investigate the correlationship with the membrance vesicle uptakes.

Keywords

References

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