Toxicological Research

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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Hygienic Quality and Safety of Gamma Irradiated Angelicae Gigantis Radix and Aloe

감마선조사에 의한 당귀와 알로에의 위생화 및 안전성 평가

  • Published : 1997.06.01
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Abstract

Gamma irradiation was applied to Angelicae gigantis radix and Aloe to improve their hygienic quality. The effective dose of irradiation was 7 kGy in Angelicae gigantis radlx and 5 kGy in Aloe for the sterilization of all contaminated microorganisms tested. After 8 months of storage at room temperature, no growth of microorganisms was observed in the irradiated products. The safety of these products were evaluated by Salmonella typhimurium reversion assay and in vivo micronucleus assay using mouse bone marrow cells. They were negative in the bacterial reversion assay with S. typhimurium TA 98, TA100, TA1535 and TA1537. In the in vivo mouse micronucleus assay, they did not show any clastogenic effect at all doses tested. These results indicate that the gamma irradiation of Angelicae gigantis radix at 12 kGy and of Aloe at 10 kGy have no genotoxic effects under these experimental conditions.

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References

  1. Mutat. Res. v.213 Screening for possible human carcinogens and mutagens: a symposium report Adler, I.D.;Ashby, J.;Wuergler, F.E.
  2. J. Food Sci. v.60 Heat-resistance of Escherichia coli O157:H7 in meat and poultry as affected by product composition Ahmed, N.M.;Conner, D.E.;Huffman, D.L.
  3. Genetic Toxicology in Principles and Methods of Toxicology(3rd Ed.) Brusick, D.;Hayes, A.W.(ed.)
  4. Federal register v.55 Irradiation of poultry FDA
  5. Laboratory Methods in Food and Dairy Microbiology Harrigan, W.F.;McCance, M. E.
  6. Scientist The micronucleus test Hayashi, M.
  7. J. Appl. Bacteriol. v.71 A brief history of heat and chemical preservation and disinfection Hugo W.B.
  8. Acceptance, Control, and Trade of Irradiated Food IAEA
  9. Food Irradiation Newsletter v.15 IAEA
  10. J. Food. Prot. v.52 Chemical and organoleptic properties of irradiated dried whole egg and egg yolk Katusin-Razem, B.;Razem, D.;Matic, S.;Mihokovic, V.;Kostromin-Soons, N.;Milanovic, N.
  11. Food Technol. v.46 Irradiated strawberries enter the U.S.market Marcotte, M.
  12. Mutat. Res. v.113 Revised methods for the Salmonella mutagenicity test Maron, D.M.;Ames, B.N.
  13. J. Food Sci. v.59 Low dose irradiation affects microbiological and sensory quality of sub-tropical seafood Poole, S.E.;Mitchell, G.E.;Mayze, J.L.
  14. Food Technol. v.46 Irradiated product reaches midwest market Pszczola, D.E.
  15. Mutat. Res. v.31 The micronucleus test Schmid, W.
  16. Compendium of Methods for the Microbiological Examination of Foods Speck, M.
  17. J. Food Sci. v.60 Radiation sensitivity of Listeria monocytogenes on beef as affected by termperature Thayer, D.W.;Boyd, G.
  18. WHO Technical Report Series, No. 659 Wholesomeness of irradiated food: Report of Jonit FAO/IAEA/WHO Expert Committee WHO
  19. A technique for preserving and improving the safety of food Food irradiation WHO