Applied Chemistry for Engineering (공업화학)

The Korean Society of Industrial and Engineering Chemistry (한국공업화학회)
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Synthesis and Biocompatibility of the Hydroxyapatite Ceramic Composites from Tuna Bone(I) - The Sintering Properties of Hydroxyapatite and Hydroxyapatite- Containing Wollastonite Crushed with Dry Milling Process -

참치 뼈를 이용한 Hydroxyapatite 세라믹 복합체의 합성 및 생체 친화성(제1보)-건식법으로 분쇄한 Hydroxyapatite 및 Wollastonite가 첨가된 소결체의 특성-

  • Kim, Se-Kwon (Dept. of Chemistry, Pukyong National University) ;
  • Lee, Chang-Kook (Dept. of Chemistry, Pukyong National University) ;
  • Byun, Hee-Guk (Dept. of Chemistry, Pukyong National University) ;
  • Jeon, You-Jin (Dept. of Chemistry, Pukyong National University) ;
  • Lee, Eung-Ho (Dept. of Food Science and Technology, Pukyong National University) ;
  • Choi, Jin-Sam (Dept. of Chemistry, Pukyong National University)
  • Received : 1997.08.30
  • Accepted : 1997.11.22
  • Published : 1997.12.10
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Abstract

The sintering properties of hydroxyapatite isolated from tuna bone and hydroxyapatite-containing wollastonite sintered by solid-state reaction was investigated. As the sinterability of hydroxyapatite dependent upon the particle size by dry milling, it showed a sintering. But the hydroxyapatite-containing wollastonite was appeared good sinterability. On X-ray measurements, the major phases of hydroxyapatite-containing wollastonite by solid state reaction at $1250^{\circ}C$ were identified as hydroxyapatite and pseudowollastonite(${\alpha}-CaSiO_3$). And the phases appeared as whitlockite [$Ca_3(PO_4)_2$] by decomposition of hydroxyapatite at higher temperature above $1250^{\circ}C$. The shapes of microstructure on SEM images changed from porous to dense bulk by elevating temperature. The mean bending strength of hydroxyapatite-containing wollastonite sintered by solid-state reaction at $1300^{\circ}C$ was about 18 MPa, it was close to the cancellous bone's maximum strength, 20 MPa.

참치 뼈로부터 추출한 hydroxyapatite [$Ca_{10}(PO_4)_6(OH)_2$] 와 여기에 소결성 증진을 위해 wollastonite($CaSiO_3$)를 첨가하여 고상반응시킨 세라믹 소결체의 결정상, 미세구조와 꺽임강도(bending strength) 등의 특성을 고찰하였다. 참치 뼈에서 추출한 hydroxyapatite자체의 소결성은 매우 취약하였는데, 이는 건식법의 입자분쇄 한계 때문으로 보인다. Hydroxyapatite에 wollastonite가 첨가된 경우 소결온도가 $1250^{\circ}C$이하에서는 hydroxyapatite와 pseudowollastonite(${\alpha}-CaSiO_3$)가 혼재된 결정상을 보였으나, 온도가 증가할수록 hydroxyapatite의 분해에 따른 whitlockite [$Ca_3(PO_4)_2$] 상이 관찰되었다. 소결온도가 $1250^{\circ}C$이하에서는 미세한 입자들과 많은 기공들이 분포하였으며, 소결온도가 증가할수록 입자의 크기는 증가하여 소결이 상당히 진행된 미세구조를 나타내었다. Wollastonite가 첨가된 소결시편의 평균 꺽임강도는 18MPa로서 해면골(cancellous bone)의 최대 꺽임강도인 20MPs에 근접한 것으로 나타났다.

Keywords

Acknowledgement

Supported by : 농림수산부

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