The Korean Journal of Physiology and Pharmacology
- Volume 2 Issue 1
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- Pages.63-68
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- 1998
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- 1226-4512(pISSN)
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- 2093-3827(eISSN)
Changes in Cytosolic $Ca^{2+}$ but not in cGMP Contents May be more Important to Nitric Oxide-Mediated Relaxation in Depolarized Vascular Smooth Muscle
- Lee, Hyun-Seok (Department of Neurosurgery, Cardiovascular Research Institute, College of Medicine, Gyeongsang National University) ;
- Chang, Ki-Churl (Department of Pharmacology, Cardiovascular Research Institute, College of Medicine, Gyeongsang National University)
- Published : 1998.02.21
Abstract
Nitric oxide (NO)-mediated relaxation in vascular smooth muscle involves not only activation of guanylate cyclase but also hyperpolarization of the membrane. It has been shown that depolarization decreases the [