Two Cases of Cryptosporidiosis in Children Confirmed by Electron Microscopy

소아에서 전자현미경으로 확진된 Cryptosporidiosis 2례

  • Chung, Ju-Young (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Bae, Sun-Hwan (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Ko, Jae-Sung (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Cho, Hui-Seung (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Seo, Jeong-Kee (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Chi, Je-Geun (Department of Pathology, Seoul National University College of Medicine) ;
  • Chai, Jong-Yil (Department of Parasitology, Seoul National University College of Medicine) ;
  • Lee, Soon-Hyung (Department of Parasitology, Seoul National University College of Medicine)
  • 정주영 (서울대학교 의과대학 소아과학교실) ;
  • 배선환 (서울대학교 의과대학 소아과학교실) ;
  • 고재성 (서울대학교 의과대학 소아과학교실) ;
  • 조희승 (서울대학교 의과대학 소아과학교실) ;
  • 서정기 (서울대학교 의과대학 소아과학교실) ;
  • 지제근 (서울대학교 의과대학 병리학교실) ;
  • 채종일 (서울대학교 의과대학 기생충학교실) ;
  • 이순형 (서울대학교 의과대학 기생충학교실)
  • Received : 1998.08.11
  • Accepted : 1998.09.08
  • Published : 1999.03.30

Abstract

Cryptosporidiosis is an intestinal disease caused by the protozoan Cryptosporidium parvum. The most common manifestation in human is enteric symptoms, which in immunocompetent hosts are self-limiting but can be life threatening in immunocompromised hosts, characterized by profuse watery diarrhea, abdominal pain, severe weight loss. It's prevalence rate in immunocompetent host is variable by geographic locations (3~11%) but up to 15~40% in AIDS patients. Now it is considered as one of the important enteropathogens causing diarrhea not only in immunocompromised but also in immunocompetent hosts, especially in children. We experienced two cases of cryptosporidiosis in a 15 year old boy who was admitted due to diarrhea, abdominal pain and fever and in a 8 year old boy who was admitted due to watery diarrhea and vomiting. These are the first clinical cases of cryptosporidiosis confirmed by electron microscopy of the colonic mucosa among immunocompetent children in Korea.

저자들은 15세 된 남아와 8세된 남아에서 C. parvum에 의한 위장관염 2례를 경험하였으며 전자 현미경상으로 확진하여 보고하는 바이다. 향후 국내에서도 소아의 설사질환의 원인으로서 cryptosporidiosis에 대한 임상의들의 많은 관심이 요구된다.

Keywords