일부 사춘기 여중생의 혈청 구리, 아연함량과 혈청 렙틴 및 지질과의 관계

The Study of Relation Among Serum Copper, Zic, Leptin and Lipids of Middl-school Girls

  • 김미현 (숙명여자대학교 식품영양학과) ;
  • 이윤신 (수원여자대학 식품과학부) ;
  • 이다홍 (숙명여자대학교 식품영양학과) ;
  • 박혜순 (울산의대 서울중앙병원 가정의학과) ;
  • 승정자 (숙명여자대학교 식품영양학과)
  • 발행 : 2001.06.01

초록

The purpose of this study was to investigate the relationship among nutritional status of copper and zinc, serum leptin, and lipids of 99 middle school girls residing in kyunggi-do, Korea. Subjects were divided assigned to one of two groups such as normal (BMI<85 percentile, n=58) and obese (85$\leq$BMI, n=41) groups. Subjects were evaluated based on anthropometric measurements, 24-hr dietary recalls and blood analysis. The mean age was 13.93 years. The mean weight (p<0.001), BMI (p<0.001), body fat (p<0.001) of obese were significantly higher then those of normal group. The mean daily energy intake was 94.2% of RDA for Korean. The ratio of energy coming from carbohydrate, fat and protein was 63:24:13. The mean daily intakes of Cu and Zn were 1.4 mg and 7.4 mg (73.7% of RDA), and there were no significant difference between two groups. The mean serum levels of leptin (p<0.001), LDL-cholesterol (p<0.05), triglyceride (p<0.01), TPH (total cholesterol/HDL; p<0.001), LPH (LDL/HDL; p<0.001) and AI (atherogenic index; p<0.001) of obese were significantly higher than those of normal group. The mean serum Cu level of obese was significantly higher than normal group but, the mean serum Zn level of obese was significantly lower than normal group. Serum Cu showed a significantly positive correlations with body weight (p<0.001), BMI (p<0.001), body fat (p<0.001), serum leptin, and LPH. However, serum Zn showed a significantly negative correlations with body weight (p<0.001), BMI (p<0.001), serum leptin (p<0.001), TPH (p<0.05), and AI (Atherogenic index; p<0.05). To summarize the results, the Zn intakes of middle school girls did not reach to RDA for Koreans. Also, increase of BMI may lead to decrease of serum zinc level and increase of serum copper level, and this change of serum zinc related to the change of serum leptin and serum lipids level in middle school girls during rapid growth.

키워드

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