Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effects of Rubi Fructus Water Extract On Oxygen Free Radical Metabolizing Enzyme Activites

복분자가 유리산소 대사효소 활성에 미치는 영향

  • Lee Kwang Gyu (College of Oriental Medicine, Woosuk University) ;
  • Cui Xun (Department of Oriental pharmacy, Woosuk University) ;
  • Lim Jong Pil (Department of Oriental pharmacy, Woosuk University)
  • Published : 2002.10.01
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Abstract

Rubi Fructus (fruit of Rubus coreanus Miq.), oriental medicine, has been used for remedy of the liver diseases and for tonic. In order to investigate the oxygen free radical, a harmful factor of aging, in liver of rats fed diets supplemented with the Rubi Fructus water extract(RX), Sprague-Dawley male rats have been fed a diet supplemented with 3% or 5% RX for a month. In rats fed 3% RX supplemented diet, hepatic cytochrome P-450 contents appeared to be increased, and catalase and superoxide dismutase activities were significantly increased compared with the control. There was no difference in glutathione peroxide and glutathione-S-transferase activities between the rats fed RX supplemented diets and the control diet. In conclusion, it is likely that rats fed a diet supplemented with RX may have the oxygen free radicals detoxication potential.

Keywords

References

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