Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effect of Insamyangyoung-tang on the Specific Immune Response in BALB/c Mice

인삼양영탕이 생쥐의 특이적 면역반응에 미치는 영향

  • Eun Jae Soon (Department of Pharmacy, Woosuk University) ;
  • Kim Dae Keun (Department of Pharmacy, Woosuk University) ;
  • Choi Hoon (Department of Oriental Pharmacy, Woosuk University) ;
  • Oh Chan Ho (Department of Biotechnology, Woosuk University)
  • Published : 2002.08.01
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Abstract

The purpose of this research was to investigate the effects of Insamyangyoung-tang water extract (IYT) on the specific immune response in BALB/c mice. When IYT (500mg/kg) was administerd p.o. once a day for 7 days to BALB/c mice, the cell viability of thymocytes and splenocytes was increased. Also, IYT increased the population of CD4/sup +/ cells in thymocytes and the population of Thy1/sup +/ cells and CD4/sup +/ cells in splenocytes. In addition, IYT increased the production of γ -interferon and interleukin-2 from thymocytes and the production of γ -interferon from splenocytes. These results suggest that IYT enhances the specific immune response via activation of Th1 cells in thymocytes and splenocytes.

Keywords

References

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