Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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The Study of KCG Extract Under the Anti-Stress Effect of Rats

가미천마구등음의 항스트레스 효과에 대한 실험적 연구

  • Park Jung Jun (Department of Oriental internal medicine, College of Oriental Medicine, Taejeon University) ;
  • Kim Dong Hee (Department of Oriental Pathology, College of Oriental Medicine. Taejeon University) ;
  • Lee Yang Gu (Department of Oriental internal medicine, College of Oriental Medicine, Taejeon University) ;
  • Kim Yoon Sik (Department of Oriental internal medicine, College of Oriental Medicine, Taejeon University) ;
  • Seol In Chan (Department of Oriental internal medicine, College of Oriental Medicine, Taejeon University)
  • 박정준 (대전대학교 한의과대학 순환기내과교실) ;
  • 김동희 (대전대학교 한의과대학 병리학교실) ;
  • 이용구 (대전대학교 한의과대학 순환기내과교실) ;
  • 김윤식 (대전대학교 한의과대학 순환기내과교실) ;
  • 설인찬 (대전대학교 한의과대학 순환기내과교실)
  • Published : 2002.04.01
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Abstract

To determine the anti-stress effect of KCG(加味天麻鉤藤飮) extract on sprague-dawley rats. we conducted a research about the change of weight, activity, reactivity, c-fos protein, cytotoxicity against PC12 cell line and heal shock protein. 1) KCG extract siginificantly inhibited the decrease of body weight induced by stress, compared with the control group. 2) KCG extract had no siginificant effect in the activity and reactivity of rats between the control and the experimental groups. 3) KCG extract siginificantly restrained c-fos protein manifestation, compared with the control group. 4) KCG extract siginificantly restrained heat shock protein, compared with the control group. These results suggested that KCG might be usefully anti-stress effect.

Keywords

References

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