Advances in Traditional Medicine

  • 제3권2호
  • /
  • Pages.80-83
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  • 2003
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  • 2662-4052(pISSN)
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  • 2662-4060(eISSN)
경희대학교 융합한의과학연구소 (Kyung Hee Oriental Medicine Research Center)
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Inhibitory effects of ethanol extract of Atractylodis Rhizoma on melanogenesis in B16/F10 melanoma cells

  • Chun, Hyun-Ja (Division of Natural Sciences, Wonkwang University) ;
  • Lee, Jeong-Ho (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Choi, Eun-Young (Department of Skin and Care, Kimcheon Science College) ;
  • Baek, Seung-Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University)
  • 발행 : 2003.05.30
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초록

The inhibitory effect of Atractylodis Rhizoma alba extract(AM) on melanogenesis was studied by using B16/F10 melanoma in culture. Cells were cultured in the presence of various concentrations of AM for 48 hrs, and the experiment of total melanin content as a final product and activity of tyrosinase, a key enzyme, in melanogenesis. AM significantly inhibited tyrosinase activity, and melanin content in a dose-dependent manner. These results show that Atractylodes macrocephala extract could be developed as skin whitening components of cosmetics.

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참고문헌

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피인용 문헌

  1. Effect of extracts of traditional Chinese medicines on anti-tyrosinase and antioxidant activities vol.9, pp.48, 2015, https://doi.org/10.5897/JMPR2015.5953