Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Antimalarial activity of marine alga aganist P. falciparum in vitro

열대열 말라리아에 대하여 항 말라리아 효과가 있는 해조류에 대한 연구

  • Kim Hye Sook (Faculty of Pharmaceutical Sciences, Okayama University, Tsushima Okayama) ;
  • Wataya Yusuke (Faculty of Pharmaceutical Sciences, Okayama University, Tsushima Okayama) ;
  • Takaya Yoshiaki (Faculty of Pharmacy, Meijo University, Yagotoyama, Tempaku-ku, Nagoya, Japan) ;
  • Ahnn Joo Hong (Department of Life Science, Kwangju Institute of Science and Technology, Kwangju) ;
  • Jeon Byung Hun (Department of Pathology, College of Oriental Medicine, Wonkwang University) ;
  • Shin Ho Joon (Department of Microbiology, Ajou University School of Medicine) ;
  • Shin Chang Ho (Department of Parasitology, College of Medicine, Wonkwang University) ;
  • Kim Yong Man (Department of Parasitology, College of Medicine, Wonkwang University) ;
  • Park Hyun (Department of Parasitology, College of Medicine, Wonkwang University)
  • 김혜숙 (오까야마대학교 약학대학) ;
  • ;
  • ;
  • 안주홍 (광주과기원 생명과학과) ;
  • 전병훈 (원광대학교 한의과대학 병리학교실) ;
  • 신호준 (아주대학교 의과대학 미생물학교실) ;
  • 신창호 (원광대학교 의과대학 기생충학교실) ;
  • 김용만 (원광대학교 의과대학 기생충학교실) ;
  • 박현 (원광대학교 의과대학 기생충학교실)
  • Published : 2003.10.01
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Abstract

To produce anti-malarial drugs, natural products were extracted from 18 species of marine algae by various mechanical methods. Twelve species of marine algae were found to have antiplasmodial activity by inhibiting the growth of the chloroquine-resistant Plasmodium falciparum strain FCR-3 with EC/sub 50/ values less than 100 ㎍/㎖. The methanol extract of Neoholmeria japonica had the strongest antiplasmodial activity with EC/sub 50/ value of 62 ㎍/㎖.

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References

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