Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
권호 표지

Effect of Maekmoondong-tang on the Immunomodulatory action

맥문동탕의 면역조절 효과

  • Kim Ho (Department of Pathology, College of Oriental Medicine, Woosuk University) ;
  • Jeong Han Sol (Department of Pathology, College of Oriental Medicine, Woosuk University) ;
  • Kwon Jin (Department of Heath Administration, Kunjang College) ;
  • Lee Kwang Gyu (Department of Pathology, College of Oriental Medicine, Woosuk University)
  • 김호 (우석대학교 한의과대학 병리학교실) ;
  • 정한솔 (우석대학교 한의과대학 병리학교실) ;
  • 권진 (군장대학교 보건행정과) ;
  • 이광규 (우석대학교 한의과대학 병리학교실)
  • Published : 2003.08.01
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Abstract

The purpose of this research was to investigate the effect of Maekmoondong-tang(MMDT) on the activity of immune cell. The addition of MMDT(10 ㎍/㎖) enhanced the proliferation of cultured-splenocytes and thymocytes. And administration of MMDT(250, 500 ㎎/㎏) accelerated subpopulation of splenic T lymphocytes in BALB/c mice. In contrast, the treatment of the high concentration (500 ㎎/㎏)of MMDT were decreased thymic T lymphocytes. Administration of MMDT(250, 500 ㎎/㎏) eminently enhanced the production of IFN-γ. And MMDT did not affect the cell viability of Jurkat leukemia cells. These results suggest that MMDT have a immunoregulatory effect via enhanced cell mediated immunity

Keywords

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