Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Experimental Study on the Anti-allergic Effects of Palmul-tang

팔물탕이 알레르기반응에 미치는 효과

  • Heo Man Kyu (Department of Oriental Medicine, Graduate School. Dongeui University) ;
  • Hong Hyun Woo (Department of Oriental Medicine, Graduate School. Dongeui University) ;
  • Kam Chul Woo (Department of Oriental Medicine, Graduate School. Dongeui University) ;
  • Park Dong Il (Department of Oriental Medicine, Graduate School. Dongeui University)
  • 허만규 (동의대학교 한의과대학 폐계내과학교실) ;
  • 홍현우 (동의대학교 한의과대학 폐계내과학교실) ;
  • 감철우 (동의대학교 한의과대학 폐계내과학교실) ;
  • 박동일 (동의대학교 한의과대학 폐계내과학교실)
  • Published : 2003.08.01
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Abstract

This experimental research has been done to study the effects of Palmul-tang on the anti-allergic reaction. We found the several important results from the research which has been performed by two experiments toward immediately type and delayed type in order to study the effects of Palmul-tang on hypersensitivity response to mice. The results obtained from our research are as following: The survival rate of one group to which we injected only the compound 48/80 is almost 0% according to its density and timing test. In the other hand. the survival rates of the other group to which we injected both of the compound 48/80 and Palmul-tang are 20%, 0%. 40%, 10%, 20% and 50% according to 0.025, 0.05, 0.1, 0.25 0.5 and 1 (mg/g) of compound 48/80. Time dependency test also shows the 30% and 20% survival rates in 5 and 10 minutes. Palmul-tang revealed the significantly inhibitory effect on Compound 48/80 induced Mast cell degranulation. Palmul-tang showed the significantly inhibitory effect in the delayed type hypersensitivity response to picry1 chloride. Palmul-tang showed the significantly inhibitory effect in the delayed type hypersensitivity response to sheep red blood cell. Our research provides the important evidence that Palmul-tang is benificial to the prevention and treatment of allergy related aiseases.

Keywords

References

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