Journal of Pharmacopuncture (대한약침학회지)

KOREAN PHARMACOPUNCTURE INSTITUTE (대한약침학회)
권호 표지
DOI QR코드

DOI QR Code

Effects of Scolopendra subspinipes multilans Herb-Acupuncture on the Carrageenan induced arthritis in rats

오공약침(蜈蚣藥針)이 Carrageenan으로 유발(誘發)된 흰 쥐의 관절염(關節炎)에 미치는 영향(影響)

  • Yu, Won-Bok (Department of Oriental Medicine, College of Oriental, Semyung University) ;
  • Soh, Kyeong-Sun (Department of Oriental Medicine, College of Oriental, Semyung University) ;
  • Jeong, Chan-Gil (Department of Oriental Medicine, College of Oriental, Semyung University) ;
  • Kim, Kwang-Ho (Department of Oriental Medicine, College of Kyung Hee University)
  • 류원복 (세명대학고 한의과대학) ;
  • 소경순 (세명대학고 한의과대학) ;
  • 정찬길 (세명대학고 한의과대학) ;
  • 김광호 (경희대학교 한의과대학 예방의학교실)
  • Published : 2004.12.30
Download PDF
⟨ Previous Next ⟩

Abstract

This study was designed to check of Scolopendra subspinipes multilans Herb-Acupucture on effect of anti-inflammtory function, anti-febrile function and analgestic function in carrageenan-induced arthritic rat. Each of 8 rat were classified into control, sample group. Control group were inject by normal saline and Sample group were injected by Scolopendra subspinipes multilans. Herb-Acupuncture. After elicitating edema and inflammation of Sprgue Dawely(SD) rats by injection of 1% Carrageenan 0.1ml, then the rate of increase of paw edema, CRP, ESR, WBC were checked and rectal-temperature, topical temperature was checked about anti-febrile. writhing syndrome was checked about analgesic. The results were as follows 1. In the sample group, the rate of increase of paw edema was significantly decreased as compared with thatof control group(P<0.05) 2. In the sample group, the rectal-temperature was non-significantly decreased as compared with that of control group (P<0.05) 3. In the sample group, CRP and WBC was significantly decreased as compared with that of control group, but ESR was not.(P<0.05) 4. In the sample group, opical-temperature was significantly decreased as compared with that of control group (P<0.05) 5. In the sample group, analgestic function was not sigiflcntly effected as compared with that of control group(P<0.05) According to the above result, it can be concluded Scolopendra subspinipes multilans Herb-Acupucture showed the treatment effects on the artifical arthritis resulted from carrageenan in rat and it is suggested that more interest and study in the mechanism and clinical use were needed.

Keywords

References

  1. 李文鎬 外 : 內科學, 서울, 금강출판사, 1979 : 1693-1698
  2. 上海中醫學院 篇. 內科學. 上海科學技術出版社. 上海. 1983 : 234-238
  3. 王顯明 : 中醫內科辨證學. 人民衛生出版社. 北京 1984 : 393-408
  4. 黃文東 外. 實用中醫內科學. 上海科學技術出版社. 上海. 1984 : 554-569
  5. 王氷 註. 黃帝內經. 고문사. 서울. 1974: 24
  6. 張機. 金匱要略. 成輔社. 서울 1985: 117-119
  7. 趙佶 外. 聖濟總錄. 人民衛生出版社. 北京 1962: 209-230
  8. 方廣 : 丹溪心法附餘. 大星出版社. 서울. 1982 : 206, 207
  9. 李東垣. 東垣十種醫書. 大星出版社. 서울 1983 : 97-98
  10. 吳搏. 醫學正傳. 人民衛生出版社. 北京. 1981. 212-213
  11. 上海中醫學院 篇. 鍼灸學. 人民衛生出版社. 北京 1974 : 450-451,459-462
  12. 金定濟. 診療要鑑(上). 東洋醫學硏究院. 서울 1974 : 450,451
  13. 全國韓醫科大學 本草學敎授. 共著. 本草學. 永林社. 1994. 서울. p.508
  14. 김창민 외. 中藥大辭典. 정담. 1998 : 3919-3923
  15. 신길구. 申氏本草學. 수문사. 1973 : 297-298
  16. 李時珍. 本草綱目(下). 수서원 1975 : 239-240
  17. Roberson, W., Van, B., and Schwartz, B. Ascorbic acid and the formation of collagen. J. biol. Chem. 1953 : 201 ;608
  18. Bonney, R. J. Gery. T., Lin, T., Meyenhofer, M, F Acevedo, W., and Davies, P. Mononuclear phagocytes from carrageenan induced granulomas. J. Exp. Med. 1977 : 148, 261 https://doi.org/10.1084/jem.148.1.261
  19. C,G. Van Arman, A.G. Begany, L.M. Miller and H.H. Pless. Some details of the inframmation caused by yeast and carrageenin. J. Phamacol. Exptl. Therap. 1965 : 150(2), 328-333
  20. 김근찬, 이명종. Adjuvant關節炎에 관한 韓醫學 論文의 分析과 最近 硏究 動向에 대한 考察. 韓方再活醫學科學會誌. 2003. Vol 13. No.3: 1-16
  21. C.A. Winter : E.A. Risley G.W. Nuss. J. Pharmacol.Exph.Therap. 141 : 369.
  22. 金井 泉 외, 臨床檢査法提要, 고문사, 1991 : 297-303
  23. Whittle B.A. : Thee use of chaanges in capillary permeability in mice to distinguish between narcotic and nonnarcotic analgesics, Brit. j. Pharmacol. 1965, p. 150, 16
  24. 柴田丸, 藤井三映子, 八木勉 : 藥學雜誌, Vol 86, 日本, 1966.
  25. 全國韓醫科大學 再活醫學科敎室. 東醫再活醫學科學. 서원당. 서울. 1995 ; 95-6
  26. 巢元方. 巢氏諸病源候論.. 昭人出版社. 臺北. 1974 : 11-12
  27. 李東垣. 東垣十種醫書. 大星文化社. 서울 1991 : 452-453, 861-865
  28. 李梃. 原本篇註醫學入門. 南山堂. 서울 1985 : 1454-1457
  29. 張介賓. 景岳全書(上). 大星文化社. 서울 1994 : 229-234
  30. 해리슨 번역 편찬위원회. Harrison`s 내과학. 정담. 서울. 1997 : 590-596,1777-1785,1816-1841.
  31. 大韓病理學會. 病理學. 高文社. 서울. 1991 : 1210-1220.
  32. Howard, C. Hopps. Principles of Pathology. New ork. Applenton Century-Cr-ofts. 1964 : 182-222
  33. Stanley. L. Robbins. Pathologic basis of disease. Pliladelphia. W.B. Saunders company. 1974 : 55-58
  34. Lowther, D.A., Gillard, D. Carrageenin-induced arthritis. 1. The effect of tntraarticular carrageenin on the chemical composition of articular cartilage. Arthr. Pheum. 976 : 19, 769 https://doi.org/10.1002/1529-0131(197607/08)19:4<769::AID-ART1780190419>3.0.CO;2-V
  35. Gardner, D.L., Production of arthritis in the rabbit by the local infection of the mucopoly-saccharide carrageenin. Ann. Rheum. 1960 ; 19, 369 https://doi.org/10.1136/ard.19.4.369
  36. 박소영 외. 蜈蚣에 대한 文獻的 考察. 대한藥針 학회지 Vol5, No.1, June 2002
  37. 홍남두. 慶熙藥大論文集. 1977 ; Vol 5 : 20-27
  38. 정병태, 장경전, 송춘호, 안창범. 蜈蚣水鍼이 鎭痛 및 鎭痙效果에 미치는 영향. 大韓針灸學會誌. 1997 ; 14(2) : 219-230
  39. 장통영, 박희수. 牛膝藥針이 Rat의 Adjuvant 關節炎에 미치는 影響. 大韓藥鍼學會誌 Vol. 2 No.1, December 1999
  40. 이연경 : 斑猫藥針이 白鼠의 Adjuvant關節炎에 미치는 影響. 大田大學校大學院 1996
  41. 김락현 : 梔子藥針이 白鼠의 Adjuvant 關節炎에 미치는 影響. 大田大學校大學院 1996
  42. 나창수. 艾灸와 麝香,牛黃, 熊膽 藥針이 白書의 Adjuvant 關節炎에 미치는 영향. 慶熙大學校大學院 1994
  43. 고강훈외. 蜈蚣藥針을 이용한 腰椎間板脫出症 治療의 臨床的 硏究. 大韓藥鍼學會誌 2002 ; 4(3) : -57
  44. 이귀녕, 권오헌. 임상병리파일. 의학문화사. 서울. 2000 : 220, 1050

Cited by

  1. The analysis of present condition and the method of medical treatment studies on Scolopendrid Herbal Acupuncture vol.9, pp.2, 2006, https://doi.org/10.3831/KPI.2006.9.2.113