Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effect of Gamidojeok-san on Hypertension

가미도적산이 고혈압에 미치는 영향

  • Sin Hwang Su (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Oh Young Seon (Hyehwa Hospital, Taejeon University) ;
  • Kim Yoon Sik (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Seol In Chan (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
  • 신황수 (대전대학교 한의과대학 심계내과학교실) ;
  • 오영선 (대전대학교 혜화병원) ;
  • 김윤식 (대전대학교 한의과대학 심계내과학교실) ;
  • 설인찬 (대전대학교 한의과대학 심계내과학교실)
  • Published : 2004.12.01
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Abstract

This study was Investigated to prove the effect of Gamidojeok-san (Jiaweidaochi-san) on the hypertension. After administer Gamidojeok-san (Jiaweidaochi-san) extract to SHR(Spontaneous Hypertensive Rat) for 5 weeks, we examined changes of blood pressure, pulse rate, aldosterone and catecholamine in serum. Results : Following results were obtained; Gamidojeok-san(Jiaweidaochi-san) showed significant antihypertensive effect. Gamidojeok-san(Jiaweidaochi-san) decreased pulse rate but insignificant. Gamidojeok-san(Jiaweidaochi-san) showed a significant decrease in the aldosterone. Gamidojeok-san(Jiaweidaochi-san) was ineffective on the dopamine. Gamidojeok-san(Jiaweidaochi-san) decreased the norepinephrine but insignificant. Gamidojeok-san(Jiaweidaochi-san) showed a significant decrease in the epinephrine. These results indicate that Gamidojeok-san(Jiaweidaochi-san) can be used in hypertension. Further study will be needed about the functional mechanism and etc..

Keywords

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