Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effects of Paljinickmohwan on the Ovulation and Ovary in Rats

팔진익모환이 백서의 배란과 난소에 미치는 영향

  • Jung Woo Suk (Department of Gynecology, College of Oriental Medicine, Wonkwang University) ;
  • Kang Young Keum (Department of Gynecology, College of Oriental Medicine, Wonkwang University) ;
  • Choi Chang Min (Department of Gynecology, College of Oriental Medicine, Wonkwang University) ;
  • Kim Song Baeg (Department of Gynecology, College of Oriental Medicine, Wonkwang University) ;
  • Yoo Sim Keun (Department of Gynecology, College of Oriental Medicine, Wonkwang University)
  • 정우석 (원광대학교 한의과대학 부인과학교실) ;
  • 강영금 (원광대학교 한의과대학 부인과학교실) ;
  • 최창민 (원광대학교 한의과대학 부인과학교실) ;
  • 김송백 (원광대학교 한의과대학 부인과학교실) ;
  • 유심근 (원광대학교 한의과대학 부인과학교실)
  • Published : 2004.10.01
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Abstract

Paljinickmohwan(八珍益母丸) is used in female infertility. especially due to deficiency of qi and blood or Qihyulyanghe(氣血兩虛). An attempt was made to evaluate the influences of PJIMH on the serum concentrations of FSH, LH, and estradiol(E2), the histological changes of ovary and the immunohistochemical staining for AT2 receptor in ovary of rats. The results of the study were as follows : Blood FSH level significantly increased in experimental group as compared with control group. In blood LH level, experimental group as compared with control group showed no efficacy. Blood E2 level significantly increased in experimental group as compared with control group. In histological observations of ovary, ovulation increased in experimental group as compared control group, which showed no efficacy. In observations of immunohistochemical staining for AT2 receptor in ovary, there is no difference between control group and experimental group. According to these results, it can be concluded that PJIMH influences ovary to increase the ovulation of rats.

Keywords

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