Effects of the Cheonggansoyo-san added Injinwiryeong-tang on Recovery from Damaged-liver and Mental-faculty Improvement in Alcoholism

청간소요산합인진위령탕의 Alcoholism에서의 간손상회복 및 학습능력향상 효과

  • Lim Jong Pil (Department of Oriental Pharmacy, Woosuk University) ;
  • Park Yeong Seo (Department of Pharmacy, Woosuk University) ;
  • Kim Hoon (Department of Fashion and Beauty Design, Konyang University)
  • 임종필 (우석대학교 한약학과) ;
  • 박영서 (우석대학교 약학과) ;
  • 김훈 (건양대학교 패션뷰티디자인학부)
  • Published : 2004.04.01

Abstract

Effects of the Cheonggansoyo-san added Injinwiryeong-tang on recovery from damaged-liver and mental-faculty improvement in alcoholism were studied using male Sprague-Dawley rats, The rats were assigned into 4 groups; normal, control and CIX group. Control group administered ethanol(25 v/v %) at a dose 3 g/kg, while CIX group administered the water extract of Cheonggansoyo-san added Injinwiryeong-tang (CIX) 30 min before treating same dose of ethanol as control group for 10 days, orally. The GOT and GPT activities of rats were checked by Reitman & Frankel method, and all groups were subjected to trials of straight channel on the 1 st day and to those of multiple T-maze during the following 3 days. The GOT and GPT activities were increased in control group, but decreased in CIX group significantly. The time required in normal group for the straight channel of the 2nd and 3rd trials was significantly shorter than that of the 1 st, while the control group showed no significance. In the time required for the multiple T-maze trials, the control group showed no significance. But in the straight or T-maze trials, the CIX group showed significant decrease in the time required against the control group.

Keywords

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