Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Pharmacological Screening of Crude Extracts from Medicinal Plants (I)

  • Oh Hyun Ju (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University) ;
  • Kwag Jung Sook (Department of Dental Hygiene, Mokpo Science College) ;
  • Kim Myung Ju (Department of Skin & Beauty, Kwangju Health Science College) ;
  • Perry Nigel B. (Plant Extracts Research Unit, New Zealand Institute for Crop & Food Research Ltd,) ;
  • Na Young Soon (Department of Chemistry, Otago University) ;
  • Kim Hyung Min (Division of Fashion & Beauty, Kyung Hee University, Department of Pharmacology, Kyung Hee University) ;
  • Baek Seung Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University)
  • Published : 2004.02.01
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Abstract

The effects of crude extracts from medicinal plants on biological activity were investigated. The crude ethanol extract of H. paucistipula inhibited the growth of the Gram positive bacterium Bacillus subtilis ATCC 19659, (2 mm inhibition zone at 150 ㎍/disc) and the dermatophyte Trichophyton mentagrophytes ATCC 28185, (7 mm inhibition zone at 150 ㎍/disc), and toxic to P388 murine leukaemia cells ATCC CCL 46 P388D1, (IC/sub 50/ 2.48 ㎍/㎖ at 75 ㎍/disc). This crude ethanol extract of H. paucistipula is the strongest antimicrobial and cytotoxic activities against P388 murine leukaemia cells ATCC CCL 46 P388D1.

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References

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