Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Improving Effect on Aatopic Dermatitis with Treatment of Selected Herbs ; Polygoni Multiflori Radix, Diospyros Kaki, ilite and its Mixture in NCNga Mice

백하수오(白何首烏), 시엽(枾葉), 일라이트 조성물의 Atopy 병태모델 치료효과

  • 박종오 (대전대학교 한의과대학 병리학교실,맑은몸한의원) ;
  • 조성익 (대전대학교 한의과대학 병리학교실) ;
  • 이용흔 ((주) 파마코디자인) ;
  • 조은진 ((주) 파마코디자인)
  • Published : 2005.02.25
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Abstract

We observed the efficacy of natural herbs and mixture in treating atopic dermatitis using anti-human IgE treated Human HMC-I cell and NCNga mice model. First, we selected three herbs, Cynonchum witfordii, Diospyros kaki, Ilite which were used to treat skin disease in Traditional Korea Medicine. Using Human HMC-I cell treated with anti-human IgE, we investigate in vitro whether each herb effects on IL-4, IL-13, $TNF-{\alpha}$ expression and $TNF-{\alpha}$, Histamine secretion value. Finally, we conducted study whether the mixture of the selected herbs is more effective than each herb which consist the mixture and control group. The results show that the mixture is better in improving atopic dermatitis condition.

Keywords

References

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