Advances in Traditional Medicine

Kyung Hee Oriental Medicine Research Center (경희대학교 융합한의과학연구소)
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In vitro antimicrobial activity of Cassia auriculata

  • Nur, I Elysha (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, University Putra Malaysia) ;
  • Somchit, MN (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, University Putra Malaysia,Laboratory of Natural Resources, Institute of Bioscience, University Putra Malaysia) ;
  • Reezal, I (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, University Putra Malaysia) ;
  • Zuraini, A (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, University Putra Malaysia) ;
  • Mutalib, AR (Department of Pathology and Microbiology, Faculty of Veterinary Medicine, University Putra Malaysia)
  • Published : 2005.03.30
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Abstract

Ethanol and aqueous extracts of Cassia auriculata were tested in vitro against fungi (Candida albicans and Microsporum canis) and bacteria (Escherichia coli, Salmonella enteriditis, Staphylococcus aureus and Bacillus subtilis). M. canis showed dose-dependent susceptibility only towards ethanol leaf and bark extracts. C. albicans, were resistant to all types of plant extracts. Results were statistically smaller to antifungal drug ketoconazole and miconazole at equivalent concentration. Both ethanol and aqueous extracts of Cassia auriculata leaves and barks exhibit antibacterial activity against S. aureus and only the ethanol extracts of leaf and bark were detected against Bacillus subtilis. The results were compared to antibacterial drugs chloramphenicol, ampicillin, penicillin G, and enrofloxacin. The antibacterial activity was statistically similar to penicillin G. Based on the current findings, it can be concluded that this plant has antimicrobial activity, which is as potent as standard antimicrobial drugs.

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References

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