Advances in Traditional Medicine

  • 제5권2호
  • /
  • Pages.124-136
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  • 2005
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  • 2662-4052(pISSN)
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  • 2662-4060(eISSN)
경희대학교 융합한의과학연구소 (Kyung Hee Oriental Medicine Research Center)
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Analgesic and antiinflammatory activity of Alstonia macrophylla and Mallotus peltatus leaf extracts: Two popular ethnomedicines of Onge, a Negrito tribe of little Andaman

  • Chattopadhyay, Debprasad (ICMR Virus Unit, Infectious Diseases & Beliaghata General Hospital) ;
  • Arunachalam, G. (ICMR Virus Unit, Infectious Diseases & Beliaghata General Hospital) ;
  • Sur, T.K. (Department of Pharmacology, Dr. B. C. Roy P.G. Institute of Basic Medical Sciences, University College of Medicine) ;
  • Bhattacharya, S.K. (ICMR Virus Unit, Infectious Diseases & Beliaghata General Hospital) ;
  • Mandal, Asit B. (Biotechnology Laboratory, Central Agricultural Research Institute)
  • 발행 : 2005.06.30
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초록

Two popular ethnomedicines of the Onge, a Negrito tribe of Andaman Islands, were evaluated for analgesic and antiinflammatory activity. The methanol extract as well as the different fractions of methanol extract of both Alstonia macrophylla and Mallotus peltatus leaves were studied using Swiss albino mice and Wistar albino rats. Acetic acid induced writhing, Tail flick and Tail immersion; Carrageenin- and Dextran-induced paw oedema tests were used. Dose-dependent analgesic and antiinflammatory activity were demonstrated for both methanol leaf extracts as well as fractions. Results were highly comparable with that of the standard drug pethidine.

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참고문헌

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피인용 문헌

  1. L.: An Ethnomedicine Used for Anti-Inflammatory and Analgesic Activity vol.2012, pp.1741-4288, 2012, https://doi.org/10.1155/2012/254849