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Evaluation of some indigenous plant extracts for antiimplantation activity in albino rats

  • 발행 : 2005.12.30

초록

In the present investigation twelve indigenous medicinal plants have been screened for their antiimplantation activity in albino rats. The plant material was subjected for soxhlation successively and separately from non-polar solvents to polar solvents i.e., petroleum ether benzene and ethanol. Out of these three extracts the petroleum ether extract of seeds of Citrus medica, aerial part of Oxalis corniculata and Tinospora cardifolia have showed maximum antiimplantation activity. Ethanol extract of leaves of Cardiospermum helicacabum, roots of Echinops echinatus, leaves of Melia azedarach, seeds of Momordica charantia and bark of Terminalia bellirica have shown maximum antiimplantation activity amongst the three extracts of each plant material screened. Though all the three extracts of seeds of Annona squamosa and leaves of Zizyphus jujube screened for antiimplantation activity, no extract has showed any loss in implantation. The details of the results obtained are discussed.

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참고문헌

  1. Anderson LL. (1972) Biology of mammalian fertilization and implantation (Eds. Maghissi KS and Hafez ESE) Thomas Springfield Illionois, pp. 372.
  2. Anonymus. (1996) In: Wealth of India: Raw materials, Vol VII, CSIR, New Delhi.
  3. Chaturvedi M, Mali PC, Dixit VP. (1995) Fertility regulation in male rats with the help of Echinops echinatus (Roxb.) root extract. J. Phyto. Res. 8, 115-118.
  4. Chaudhury RR. (1966) Plants with possible activity, ICMR, Special Report Series, New Delhi, 5.
  5. Fisher. (1936) Satatistical method for research workers, Ed. 6, Edinburg.
  6. Garg SK. (1976) Antifertility screening of plants effect of four indigenous plants on early pregnancy in female albino rats. Indian J. Med. Res. 64, 1133.
  7. Garg SK, Mathur VS, Choudhury RR. (1978) Screening of Indian Plants for Antifertility activity. Indian J. Exp. Biol. 16, 1077.
  8. Hafez ESE. (1970) In: Reproduction and breeding techniques for laboratory animals. Philadelphia: Lea and Febiger, pp. 32.
  9. Hariharan S. (1980) Laboratory animals information service center news ICMR, Hyderabad.
  10. Kapoor M, Garg SK, Mathur VS.(1974) Antiovulatory activity of five indigenous plants in rabbits. Indian J. Med. Res. 62, 1225.
  11. Kirtikar KR, Basu AD. (1935) In Indian Medicinal Plants. Vol I, pp.792. Lalit Mohan Basu, Allahabad.
  12. Murthy DRK, Reddy CM, Patil SB. (1997) Effect of benzene extract of H. rosa sinensis on the estrous cycle and ovarian activity in albino mice. Biol. Pharm. Bull. 20, 756-758.
  13. Patel NK, Patel NK. (2004) Study of abortifacient plants used by Adivasi of ambaji area in Danta taluka in Gujarat. Ad. Plant Sci. 17, 37-40.
  14. Satyavati GV. (1984) Indian plants and plant products with antifertility effects. Current Research in Pharmacology in India. Indian J. Med. Res. 199.
  15. Sharanabasappa A, Vijaykumar B, Patil SB. (2002) Effect of Momordica charantia seed extracts on ovarian and uterine activities in albino rats. Pharmceutic. BioI. 40, 501-507. https://doi.org/10.1076/phbi.40.7.501.14688
  16. Sharanabasappa A, Vijaykumar B, Patil SB. (2003) Antispermatogenic and antiandrogenic activities of various extracts of Melia azedarach Linn. seeds in albino rats. Orient. Pharm. Exp. Med. 3, 133-140. https://doi.org/10.3742/OPEM.2003.3.3.133
  17. Snedecor CW. (1946) Statistical methods, Iowa state college press, Amer. Iowa special report series No. 55.
  18. Wiest WG, Kidwell WR, Balogh K. (1964) Progesterone catabolism in the rat ovary a regulatory mechanism for progestational potency during pregnancy. Endocrinology 82, 544-854.