Abstract
The expression of uncertainty applied to the chemical analysis is highly recommended with increasing demands upon the systematic quality assurance and control(QA/QC) with ISO 17025. For the quantification of quality source, 7 major common sources of uncertainty, normally contributing to the quality of the chemical analysis, were selected from QA/QC literatures of chemical analysis. They were classified into repeatability, drift, uncertainty in standards, linearity of calibration, homogeneity, stability of sample, and matrix effect. And, the quantification of the sources by means of measurement uncertainty was proposed as a prerequisite steps for QA/QC. Examples applied to the quantification procedures of modelling, combination and expression of standard uncertainty for the 7 major common sources were presented as a reference guide for QA/QC in chemical analysis.
화학분석 분야에는 ISO 17025에 따른 체계적 품질 관리/보증의 요구가 커지면서, 측정 불확도의 표기가 크게 요구되고 있다. 측정품질의 정량화를 위하여, 화학분석의 QA/QC 문헌들로부터 화학분석 품질에 영향을 미치는 중요한 불확도 요소를 선정하였고, 이것을 측정결과 평가 요소의 기본인 7개의 품질요소로서 반복성, 직선성, 소급성, 변동성, 매질효과, 균질성, 안정성으로 구분하였다. 화학분석의 QA/QC를 위한 이 7대 품질 요소의 측정 모델화, 표준불확도의 계산 및 합성방법을 각각 예로서 제시하였다.
