Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
권호 표지

Effect of 'Sexiang Shuhuo Jing' for CPK, LDH Activities and Skeletal Muscle ${\alpha}-actin$ mRNA Expression after Skeletal Muscle in Rats

골격근 손상에 대한 '사향서활정'(麝香舒活精)치료의 혈청 CK, LDH활성도 및 골격근 ${\alpha}-actin$ mRNA 발현 변화의 관찰

  • Kim, Jin-Hang (College of Physical Education, Hanyang University) ;
  • Song, Je-Ho (Department of Beauty Design College of Human Enviornamental Science Wonkwang University)
  • 김진항 (한양대학교 체육대학) ;
  • 송제호 (원광대학교 생활과학대학 뷰티디자인학부)
  • Published : 2006.08.25
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Abstract

The study examined clinical effect of the 'Sexiang Shuhuo Jing' on serum CK and LDH activities and skeletal muscle ${\alpha}-actin$ mRNA expression concentration 140days after skeletal muscle injury in rats. The clinical research consisted of observing and measuring the serum CK, LDH activities and skeletal muscle ${\alpha}-actin$ mRNA expression, at the time of injury and during recovery. All experimental data were analyzed by repeated measurement with ANOVA on of SPSS(11.5v), accepting level for all significances was above ${\alpha}\;=.05.$ The results were as follows: That skeletal muscle injury in rats there existed a substantial increase serum CK, LDH activities and expression of skeletal muscle ${\alpha}-actin$ mRNA And Sexiang Shuhuo Jing treatment group's serum CK, LDH activities lower and faster recovery than control group. The 1 st day after skeletal muscle injury, Sexiang Shuhuo Jing treatment group's skeletal muscle ${\alpha}-actin$ mRNA expression was much more higher than control group, after 2 day's faster recovery normal level than control group. There existed a substantial increase again serum CK, LDH activities and skeletal muscle ${\alpha}-actin$ mRNA expression 3rd days after injury in control group. But in Sexiang Shuhuo Jing treatment group's can't be found that.

Keywords

References

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