Advances in Traditional Medicine

  • 제6권1호
  • /
  • Pages.53-57
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  • 2006
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  • 2662-4052(pISSN)
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  • 2662-4060(eISSN)
경희대학교 융합한의과학연구소 (Kyung Hee Oriental Medicine Research Center)
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Protective effect of Indigofera aspalathoides in chemical induced gastric mucosal lesions in rats

  • Gupta, M (Department of Pharmaceutical Technology, Jadavpur University) ;
  • Mazumder, UK (Department of Pharmaceutical Technology, Jadavpur University) ;
  • Haldar, PK (Gupta college of Technological Sciences) ;
  • Kander, CC (Gupta college of Technological Sciences) ;
  • Manikandan, L (Department of Pharmaceutical Technology, Jadavpur University) ;
  • Senthilkumar, GP (Department of Pharmaceutical Technology, Jadavpur University)
  • 발행 : 2006.03.30
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초록

The plant Indigofera aspalathoides is used by a large number of tribes in India for the treatment of various hepatic disorders and abscesses. The methanol extract of Indigofera aspalathoides (MEIA) was evaluated for its protective effects on gastric mucosal lesion in Wister albino rats against indomethacin, histamine and ethanol induced gastric mucosal damage. The response to MEIA was assessed using the ulcer index, thiobarbituric acid reactive substance (TBARS), and glutahione level. MEIA pretreatment showed protection against chemical induced gastric mucosal damage, a significant reduction in the ulcer index and TBARS activity and increase glutathione level as compared with that of standard drugs.

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피인용 문헌

  1. Effect of Dioscorea Rhizoma on Gastritis by Acute Gastric Ulcer in Rats vol.28, pp.1, 2015, https://doi.org/10.7732/kjpr.2015.28.1.001