Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Trichomonicidal Activity of Herbal Extracts Used in Traditional Medicine in Korea

  • Kim Youn-Chul (College of Pharmacy, Wonkwang University) ;
  • Ryu Jae-Sook (Department of Parasitology, College of Medicine, Hanyang University) ;
  • Kim Hyoung-Jun (Department of Orthopedic surgery, Okayama University) ;
  • Choi Kyung-Min (Department of Infection Biology, College of Medicine, Wonkwang University) ;
  • Kim Hye-Sook (Faculty of Pharmaceutical Science, Okayama University) ;
  • Park Hyun (Department of Infection Biology, College of Medicine, Wonkwang University)
  • Published : 2006.02.01
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Abstract

Trichomonicidal activity of thirty methanolic herbal extracts used in traditional medicine in Korea was evaluated. Trichomonas vaginalis was used as experimental model, and anti-Trichomonas activity was determined over cultures of the parasite in TYM Diamond medium. Six methanolic extracts such as Acanthopanacis Cortex, Agrimoniae Herba, Pulsatillae Radix, Sanguisorbae Radix, Sophorae Radix, and Torilidis Fructus showed more than 50% trichomonicidal activity at the concentration of 200 g/ml. These extracts were further fractionated into n-butanol soluble and aqueous phases. Except for Acanthopanacis Cortex, all of n-butanol soluble phases showed potent trichomonicidal activity, while none of aqueous phases exhibited trichomonicidal activity.

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References

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