In Vitro Evaluation of Cholesterol Reduction by Lactic Acid Bacteria Extracted from Kimchi

김치 젖산균의 In Vitro에서 콜레스테롤 저하 효과

  • Kim, Gum-Ran (Department of Food Science and Nutrition, Anyang University) ;
  • Kim, Mi-Jung (Department of Food Science and Nutrition, Anyang University)
  • 김금란 (안양대학교 식품영양학과) ;
  • 김미정 (안양대학교 식품영양학과)
  • Published : 2006.12.30

Abstract

It has been recognized that high level of serum cholesterol is a risk factor associated with atherosclerosis and coronary heart disease. Ingestion of probiotic lactic acid bacteria(LAB) in Kimchi would possibly be a method to decrease serum cholesterol in humans, as it was reported. In vitro culture experiment evaluated the effects of LAB(Leu. citreum, Lac. plantarum, Leu. mesenteroides, Weissella kimchii, W. confusa) extracted from Kimchi on cholesterol reduction in the MRS broth containing soluble cholesterol. Experimental strain of Leu. citreum and Leu. mesenteroides dominated in the first phase of Kimchi fermentation reduced the level of cholesterol 55.64% and 56.37%, respectively. Also, cholesterol lowering-effect was observed in over 55% of Lac. plantarum, W. kimchii and W. confusa strains, which were dominated in the end phase of fermentation. Our results suggest that selected probiotic LAB from Kimchi have an excellent cholesterol reducing effect in in vitro culture.

본 연구는 김치에 분포하는 것으로 알려져 있는 대표적인 젖산균에 관한 콜레스테롤 저하 효과에 관하여 연구하였다. Lactobacillus 1종, Leuconostoc 2종과 Weissella 2종을 대상으로 콜레스테롤 저하 효과를 측정하였다. 김치 초기 발효균인 Leu. citreum은 55.46% 콜레스테롤 감소율을 보였고, 대표적인 산패균인 Lac. plantarum은 55.91%, Leu. mesenteroides은 56.37%였으며 W. kimchii,, W. confusa 등에서도 55% 이상의 콜레스테롤 저하 효과가 나타났다. 김치의 발효 숙성 과정에 나타나는 젖산균들이 시험관 내에서 콜레스테롤 저하 효과가 확인되어, 향후 in vivo 조건하에서 콜레스테롤 저하에 어느 정도 영향을 미치는지 검토해볼 필요가 있다고 사료된다.

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