Antibacterial Activity against the Streptococcus mutans and Anti-inflammatory Effect of Lophatheri Herba

담죽엽의 충치균에 대한 항균활성 및 항염효과

  • 전훈 (우석대학교 약학대학) ;
  • 박영서 (우석대학교 약학대학) ;
  • 강인탁 (우석대학교 약학대학) ;
  • 최훈 (우석대학교 약학대학) ;
  • 이태규 (외식산업조리학과) ;
  • 김훈 (건양대학교 미용학과) ;
  • 임종필 (우석대학교 약학대학)
  • Published : 2006.12.25

Abstract

Lophatheri Herba of Lophatherum gracile Bronghiart(Gramineae) has long been used for treatment of inflammation, fever and edema in Korea. In order to investigate antibacterial activity of the Lophatheri Herba against Streptococcus mutans ATCC27351, paper disc test and pH check were carried out with 80% ethanol extract of Lophatheri Herba(LEX). The LEX showed significant antibacterial activity. And at the dose of 50 mg/kg, LEX showed signifiant inhibition on the paw edema, vascular permeability and myeloperoxidase activity in rat's paw tissue. These results indicate that LEX has antibacterial activity against the Streptococcus mutans and anti-inflammatory effect.

Keywords

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