A Metastatic Giant Cell Tumor of the Soft Tissue of the Thoracic Wall - A case report -

흉벽 연부조직에 발생한 전이성 거대세포종 - 1예 보고 -

  • Shin, Duk-Seop (Department of Orthopaedic Surgery, Yeungnam University College of Medicine) ;
  • Lee, Jang-Hoon (Department of Thoracic and Cardiovascular Surgery, Yeungnam University College of Medicine) ;
  • Choi, Jun-Hyuk (Department of Pathology, Yeungnam University College of Medicine) ;
  • Chung, Tae-Eun (Department of Thoracic and Cardiovascular Surgery, Yeungnam University College of Medicine)
  • 신덕섭 (영남대학교 의과대학 정형외과학교실) ;
  • 이장훈 (영남대학교 의과대학 흉부외과학교실) ;
  • 최준혁 (영남대학교 의과대학 병리학교실) ;
  • 정태은 (영남대학교 의과대학 흉부외과학교실)
  • Published : 2007.07.05

Abstract

A giant cell tumor of bone is a benign bone tumor, but has very high local recurrence rate and, very rarely metastasizes to the lung or a distant area. We report a case of a 29-year-old male patient presenting with a metastatic giant cell tumor of the soft tissue of the chest wall, who underwent a total resection of the radius for recurrence of the giant cell tumor. The tumor was not related to any bony structure of the thorax. We resected the tumor with a wide surgical margin. No evidence of malignancy was seen in the frozen and permanent pathological report.

골조직에 발생하는 거대세포종은 국소적으로는 양성이지만 재발률이 매우 높고, 아주 드물게 원격전이를 일으킬 수 있다. 우측 요골에 발생한 거대세포종이 치료 후 재발되어, 요골을 제거한 후, 다시 동측 흉벽 연부조직에 전이된 29세의 남자환자를 보고하는 바이다. 종양은 흉벽의 골조직과는 연관이 없었다. 수술은 주위 연부조직과 함께 광범위 절제하였으며, 조직학적 검사상 악성 종양을 시사하는 소견은 없었다.

Keywords

References

  1. Kim JP, Park MJ, Ha SH. Giant cell tumors of tendon sheath: operative findings and relation to recurrence. J Korean Soc Surg Hand 2005;1:20-5
  2. Campanacci M, Baldini N, Boriani S, Sudanese A. Giantcell tumor of bone. J Bone Joint Surg Am 1987; 69:106-14 https://doi.org/10.2106/00004623-198769010-00018
  3. Mori Y, Tsuchiya H, Karita M, Nonomura A, Nojima T, Tomita K. Malignant transformation of a giant cell tumor 25 years after initial treatment. Clin Orthop Relat Res 2000;381:185-91 https://doi.org/10.1097/00003086-200012000-00022
  4. Eckardt JJ, Grogan TJ. Giant cell tumor of bone. Clin Orthop Relat Res 1986;204:45-58
  5. Shin JS, Lee IS, Kim AR, Kim BH. Giant cell tumor originating from the anterior arc of the rib. J Korean Med Sci 2002;17:849-51 https://doi.org/10.3346/jkms.2002.17.6.849
  6. Chang JW, Min SK, Han JJ, Park YS, Ahn JH, Won TH. Primary giant cell tumor of rib-unusual location. Korean J Thorac Cardiovasc Surg 2002;35:251-3
  7. Connel D, Munk PL, Lee MJ, et al. Giant cell tumor of bone with selective metastases to mediastinal lymphnodes. Skeletal Radiol 1998;27:341-5 https://doi.org/10.1007/s002560050394