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Short Communication Antinociceptive activity of Avicennia officinalis

  • Shahid, IZ (Pharmacy Discipline, Khulna University) ;
  • Karmakar, D (Pharmacy Discipline, Khulna University) ;
  • Sadhu, SK (Pharmacy Discipline, Khulna University) ;
  • Ahmed, F (Pharmacy Discipline, Khulna University)
  • Published : 2007.03.31

Abstract

The crude ethanol extract of leaves of Avicennia officinalis Linn. (Family: Avicenniaceae) was screened for its antinociceptive activity. The extract produced significant writhing inhibition in acetic acid-induced writhing in mice at the oral dose of 250 and 500 mg/kg body weight (P < 0.001) comparable to the standard drug diclofenac sodium at the dose of 25 mg/kg of body weight. The result tends to suggest the antinociceptive activity of the extract.

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References

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