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A Comparison of Antimicrobial Effect of Two Waterless Alcohol-based Hand Rubs with a Povidone-Iodine Hand Scrub for Surgical Hand Antisepsis

두 가지 알코올제제 손마찰과 포비돈 아이오다인의 외과적 손소독 효과 비교

  • Ju, Houng Ley (Department of Nursing, Incheon Christian Hospital) ;
  • Jeong, Jae Sim (Department of Clinical Nursing, University of Ulsan) ;
  • Kim, Mi Na (Department of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center) ;
  • Park, Kwang Ok (Children's Hospital Nursing Team, Asan Medical Center)
  • 주형례 (인천기독병원) ;
  • 정재심 (울산대 의대 임상전문간호학) ;
  • 김미나 (서울아산병원 진단검사의학과) ;
  • 박광옥 (서울아산병원 소아청소년병원 간호부)
  • Received : 2009.01.29
  • Accepted : 2009.02.27
  • Published : 2009.04.30

Abstract

Purpose: The purpose of this study was to compare the 1% chlorhexidine gluconate/61% ethanol (CHG/ethanol), 45% ethanol/18% 1-propanol (ethanol/propanol) and 7.5% povidone-iodine (PVI) scrub with brush to evaluate their antimicrobial effect. Method: Utilizing repeated measures design, 9 nurses participated in the study. Glove juice sampling procedure was used to evaluate microbial hand counts before the surgical hand antisepsis, one minute after hand wash, and after the surgery. Results: Waterless rub using CHG and ethanol combination resulted in a 3.94 log reduction at 1 min and 2.78 log reduction at 3 hrs. Ethanol/propanol resulted in a 2.42 at 1 min and 2.22 at 3 hrs. The traditional scrub using PVI with brush resulted in a 0.94 at 1 min and 0.95 at 3 hrs (p=.003) and 3 hrs (p=.026) after the surgical hand antisepsis. Repeated measures ANOVA results showed that there was a statistically significant difference among group (p=.002). Duncan post hoc test result showed that the PVI was less effective (p<.05) in sterilizing microbials on hands than CHG/ethanol or ethanol/propanol. Conclusion: Both of the two alcohol-based antiseptic rubs are acceptable alternatives to the PVI with brush for surgical hand antisepsis.

Keywords

References

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