Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effect of Sacchromyces cerevisiae-Fermented Artemisiae Argi Folium on Nitric oxide Production of Macrophage Treated with Toxicants

  • Park, Wan-Su (Department of Pathology, College of Oriental Medicine, Kyungwon University)
  • Published : 2009.08.25
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Abstract

The effects of Sacchromyces cerevisiae-Fermented Artemisiae Argi Folium Water extract (AFS) on Nitric oxide production from mouse macrophage Raw 264.7 cells treated with EtOH, gallic acid, Nicotine, Acetaminophen, and Acetaldehyde were investigated through this study. AFS (0, 10, 50, 100, 200, 400 ug/mL) was simultaneously treated with EtOH (100 uM), gallic acid (100 uM), Nicotine (1 mM), Acetaminophen (2 mM), and Acetaldehyde (200 uM). And Nitric oxide production from Raw 264.7 cells was measured by Griess reagent method. AFS restorated the cellular production of Nitric oxide reduced by EtOH, gallic acid, Nicotine, and Acetaminophen in Raw 264.7 cells. AFS could be supposed to have the immuno-modulating activity concerned with macrophage's production of Nitric oxide.

Keywords

References

  1. Editorial Committee for Collaborative Text of Oriental Medical College in the Whole Country. Bon-Cho-Hak. Seoul, Korea, A book concern of Young-Lim, pp 405-407, 1991
  2. Heo, J. Dong-Ui-Bo-Gam. Seoul, Korea, A book concern of You-Gang, p 2758, 1994
  3. Zhang, E.Q. The Chinese Materia Medica in A Practical English-Chinese Library of TCM. Shanghai, Chinal, Publishing House of Shanghai College of Traditional Chinese Medicine, p 284, 1990
  4. Oboh, G., Oladunmoye, M.K. Biochemical changes in micro-fungi fermented cassava flour produced from low- and medium-cyanide variety of cassava tubers. Nutrition and Health. 18: 355-367, 2007 https://doi.org/10.1177/026010600701800405
  5. Beiroti, A., Hosseini, S.N. Production of baker's yeast using date juice. Sheng Wu Gong Cheng Xue Bao. 23(4):746-750, 2007
  6. Nathan, C.F., Hibbs, J.B. Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr Opin Immunol. 3: 6570, 1991
  7. MacMicking, J., Xie, Q.W., Nathan, C. Nitric oxide and macrophage function. Annu Rev Immunol. 15: 323-350, 1997 https://doi.org/10.1146/annurev.immunol.15.1.323
  8. Goldsby, R.A., Kindt, T.J., Osborne, B.A., Kuby, J. Immunology (5th ed.). New York, USA, W.H. Freeman and Company. pp 38-39, 2003
  9. Kim, M.J., Kim, D.H., Lee, K.W., Yoon, D.Y., Surh, Y.J. Jaceosidin induces apoptosis in ras-transformed human breast epithelial cells through generation of reactive oxygen species. Ann N Y Acad Sci. 1095: 483-495, 2007 https://doi.org/10.1196/annals.1397.052
  10. Jeong, M.A., Lee, K.W., Yoon, D.Y., Lee, H.J. Jaceosidin, a pharmacologically active flavone derived from Artemisia argyi, inhibits phorbol-ester-induced upregulation of COX-2 and MMP-9 by blocking phosphorylation of ERK-1 and -2 in cultured human mammary epithelial cells. Ann N Y Acad Sci. 1095: 458-466, 2007 https://doi.org/10.1196/annals.1397.049
  11. Shoemaker, M., Hamilton, B., Dairkee, S.H., Cohen, I., Campbell, M.J. In vitro anticancer activity of twelve Chinese medicinal herbs. Phytother Res. 19(7):649-651, 2005 https://doi.org/10.1002/ptr.1702
  12. Lee, H.G., Yu, K.A., Oh, W.K., Baeg, T.W., Oh, H.C., Ahn, J.S., Jang, W.C., Kim, J.W., Lim, J.S., Choe, Y.K., Yoon, D.Y. Inhibitory effect of jaceosidin isolated from Artemisiaargyi on the function of E6 and E7 oncoproteins of HPV 16. J Ethnopharmacol. 98(3):339-343, 2005 https://doi.org/10.1016/j.jep.2005.01.054
  13. Weissman, B.A., Gross, S.S. Measurement of NO and NO synthase. Current Protocols in Neuroscience. 7: 13, 2001
  14. Adams, M., Efferth, T., Bauer, R. Activity-guided isolation of scopoletin and isoscopoletin, the inhibitory active principles towards CCRF-CEM leukaemia cells and multi-drug resistant CEM/ADR5000 cells, from Artemisia argyi. Planta Med. 72(9):862-864, 2006 https://doi.org/10.1055/s-2006-947165
  15. Lee, S.H., Kim, H.K., Seo, J.M., Kang, H.M., Kim, J.H., Son, K.H., Lee, H., Kwon, B.M., Shin, J., Seo, Y. Arteminolides B, C, and D, new inhibitors of farnesyl protein transferase from Artemisia argyi. J Org Chem. 67(22):7670-7675, 2002 https://doi.org/10.1021/jo020299z
  16. Tan, R., Jia, Z. Eudesmanolides and Other Constituents from Artemisia argyi. Planta Med. 58(4):370-372, 1992 https://doi.org/10.1055/s-2006-961488
  17. Yin, Y., Gong, F.Y., Wu, X.X., Sun, Y., Li, Y.H., Chen, T., Xu, Q. Anti-inflammatory and immunosuppressive effect of flavones isolated from Artemisia vestita. J Ethnopharmacol. 120(1):1-6, 2008 https://doi.org/10.1016/j.jep.2008.07.029
  18. Lv, W., Sheng, X., Chen, T., Xu, Q., Xie, X. Jaceosidin induces apoptosis in human ovary cancer cells through mitochondrial pathway. J Biomed Biotechnol. 2008: 394802, 2008
  19. Lee, S.H., Kim, H.K., Seo, J.M., Kang, H.M., Kim, J.H., Son, K.H., Lee, H., Kwon, B.M., Shin, J., Seo, Y. Arteminolides B, C, and D, new inhibitors of farnesyl protein transferase from Artemisia argyi. J Org Chem. 67(22):7670-7675, 2002 https://doi.org/10.1021/jo020299z
  20. Tan, R., Jia, Z. Eudesmanolides and Other Constituents from Artemisia argyi. Planta Med. 58(4):370-372, 1992 https://doi.org/10.1055/s-2006-961488
  21. Bogdan, C., Rollinghoff, M., Diefenbach, A. The role of nitric oxide in innate immunity. Immunol Rev. 173: 17-26, 2000 https://doi.org/10.1034/j.1600-065X.2000.917307.x