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Clinical Analysis of Contralateral Bulla of Lung on HRCT in the Patients Having Video-Assisted Thoracoscopic Surgery for Unilateral Primary Spontaneous Pneumothorax

자연 기흉 수술 환자에서 반대편 폐기포에 대한 임상적 고찰

  • Shin, Dong-Il (Department of Thoracic and Cardiovascular Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Oh, Tae-Yoon (Department of Thoracic and Cardiovascular Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Chang, Woon-Ha (Department of Thoracic and Cardiovascular Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Kim, Jung-Tae (Department of Thoracic and Cardiovascular Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Jeong, Young-Kyun (Department of Thoracic and Cardiovascular Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine)
  • 신동일 (성균관대학교 의과대학 강북삼성병원 흉부외과학교실) ;
  • 오태윤 (성균관대학교 의과대학 강북삼성병원 흉부외과학교실) ;
  • 장운하 (성균관대학교 의과대학 강북삼성병원 흉부외과학교실) ;
  • 김정태 (성균관대학교 의과대학 강북삼성병원 흉부외과학교실) ;
  • 정영균 (성균관대학교 의과대학 강북삼성병원 흉부외과학교실)
  • Received : 2010.08.24
  • Accepted : 2010.11.16
  • Published : 2010.12.05

Abstract

Background: It is controversial whether the presence of bullae on the contralateral lung on HRCT plays a role in occurrence of contralateral primary spontaneous pneumothorax. We analyzed the significance of bullae on the contralateral lung and the risk factors associated with contralateral occurrence of primary spontaneous pneumothorax. Material and Method: Three hundred ninety four patients who were undergone Video-Assisted Thoracoscopic Surgery for primary spontaneous pneumothorax between January 2004 and December 2009 were reviewed. The clinical features, HRCT and treatment of these patients were analyzed retrospectively. Result: Twenty eight of 394 patients had contralateral occurrence (7.10%). The average time was $13.06{\pm}9.79$ months. A presence of contralateral bullae of lung on HRCT may not seem to be significant for occurrence of contralateral primary spontaneous pneumothorax (p=0.059). But bullae numbers were much more in contralateral pneumothorax patients (p=0.011). Younger than 20, being underweight (Body Mass Index < $18.5 kg/m^2$) are independent risk factors for contralateral occurrence (odds ratio, 5.075 (1.679~5.339), 2.366 (1.048~5.339) respectively). Conclusion: The presence of bullae on the contralateral lung on HRCT was not significantly influenced the occurrence of contralateral primary spontaneous pneumothorax. However, age, body mass index, and the number of bullae were significant factors for the contralateral pneumothorax. We suggest that those high risk patients may require special attentions and general supportive care to prevent occurrence of contralateral primary spontaneous pneumothorax during the follow-up.

배경: 자연 기흉으로 수술한 환자의 고해상도 CT에 보이는 반대편 기포 유무가 반대편 기흉 발생에 어떤 영향이 있는지 아직도 논란이 되고 있다. 저자들은 고해상도 CT에 보이는 반대편 기포 유무가 기흉 발생에 어떤 영향이 있는지와 기흉 발생의 위험 인자가 무엇인지에 대하여 연구하였다. 대상 및 방법: 2004년 l월부터 2009년 12월까지 본원에서 흉강경을 이용하여 수술 받은 자연 기흉 환자 394명을 대상으로 하였다. 이들 환자의 임상상과 고해상도 CT, 그리고 치료법에 대하여 후향적으로 조사하였다. 결과: 394명 중 28명 (7.10%)에서 반대편에 기흉이 발생했다. 발생까지의 기간은 13.06 (${\pm}9.79$) 개월이었다. 반대편에 기포의 유무가 반대편 자연 기흉 발생에 통계적으로 유의한 차이는 없으나(p=0.059) 반대편에 자연 기흉이 발생한 군에서 더 많은 기포수를 갖는 것으로 나타났다(p=0.011). 성별, 흡연 여부는 통계적으로 유의하지 않았다. 10대의 젊은 연령과 $18.5kg/m^2$ 이하의 체질량 지표가 통계적으로 유의하였으며 독립적 인 위험 인자로 나타났다(표본오차비율=0.04, 0.038, 0.00 각각). 결론: 자연 기흉으로 비디오 흉강경 수술 시행 받은 환자에서 고해상도CT에 보이는 기포와 크기는 반대편 자연 기흉의 발생에 영향이 없었다. 하지만 반대편 기흉이 발생한 군에서 기포수가 증가하는 경향이었고 10대인 젊은 연령과 체질량 지표가 $18.5kg/m^2$ 이하라는 위험 요인을 갖고 있었다. 따라서 이러한 환자들에 대하여는 외래 경과 추적 관찰을 자주하여 세심한 주의와 대중적인 치료가 필요할 것으로 판단된다.

Keywords

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