Journal of Chest Surgery

The Korean Society for Thoracic and Cardiovascular Surgery (대한심장혈관흉부외과학회)
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Outcome of Limited Resection for Lung Cancer

  • Cho, Jeong-Su (Department of Thoracic and Cardiovascular Surgery, Pusan National University Hospital) ;
  • Jheon, Sang-Hoon (Department of Thoracic and Cardiovascular Surgery, Seoul National University College of Medicine) ;
  • Park, Sung-Joon (Department of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital) ;
  • Sung, Sook-Whan (Department of Thoracic and Cardiovascular Surgery, Seoul National University College of Medicine) ;
  • Lee, Choon-Taek (Department of Thoracic and Cardiovascular Surgery, Seoul National University College of Medicine)
  • Received : 2010.07.19
  • Accepted : 2010.09.16
  • Published : 2011.02.05
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Abstract

Background: Up to now, lobectomy, bilobectomy and pneumonectomy combined with extensive lymph node dissection have been regarded as the standard procedures for non-small cell lung cancer (NSCLC). In high-risk patients, however, limited resection (LR) has been attempted as a salvage procedure, and, recently, indication for LR has been extended to selected cases with early-stage NSCLC. Material and Methods: Among the 773 patients who underwent surgical procedures for NSCLC in Seoul National University Bundang Hospital from May 2003 to December 2008, 43 patients received LR. Medical records of these patients were retrospectively reviewed. Results: Mean age at operation was $66.0{\pm}12.4$ years, and there were 30 males. Twenty-five patients underwent conservative limited resection (CLR) and 18 underwent intentional limited resection (ILR). Indications for CLR were multiple primary lung cancer in 9 (9/25, 36%) and severe concomitant diseases in 5 (5/25, 20%). Of these, 6 patients underwent segmentectomy and 19 received wedge resection. During the follow-up period of $28.0{\pm}17.8$ months, 15 patient developed recurrent lung cancer. ILR was selectively performed in lesions almost purely composed of ground glass opacity (${\geq}$95%), or in small solid lesions (${\leq}$2 cm). Of these, 11 patients underwent segmentectomy and 7 underwent wedge resection. During the follow-up period of $31.7{\pm}11.6$ months, no patient developed recurrence. Conclusion: Intermediate-term outcome of LR for early-stage lung cancer is comparable to that of standard operation. For the delineation of the indications and appropriate surgical techniques for LR, prospective randomized multi-institutional study may be expedient.

Keywords

Acknowledgement

Supported by : Seoul National University Bundang Hospital

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