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Risk Factors of Breast Cancer among Women in Eastern India: A Tertiary Hospital Based Case Control Study

  • Published : 2012.10.31

Abstract

Aim: Breast cancer is one of the most common cancers of women in India with high fatality rate. Over a 1 year study period 105 consecutive biopsy or fine needle aspiration cytology confirmed breast cancer patients were interviewed by direct questionnaire method regarding risk factors attending Surgery and Radiotherapy OPD of Medical College Kolkata, West Bengal while taking other 105 patients attending Surgery Department for some other disease as controls. The data were compiled in MS Excel 2007 and analyzed by Epi info 3.5.1 software. Among the cases, rural residence, illiteracy and low socio-economic status was significantly higher than controls. Late onset of menarche, late onset of menopause, ever OCP usage, breast feeding for 1-2 years and age of 1st childbirth between 20-30 years were found to be significant protective factors. People should be made aware regarding the modifiable risk factors to prevent breast cancer.

Keywords

References

  1. American Cancer Society; Breast Cancer Facts and Figures 2003-2004. Atlanta GA, USA.
  2. Donegen WL, Spratt JS (2002). Cancer of the Breast, 5th Ed, Philadelphia, WB Saunders 2002.
  3. Gajalakshmi CK, Shanta V (1991). Risk factors for female breast cancer. A hospital-based case-control study in Madras, India. Acta Oncol, 30, 569-74. https://doi.org/10.3109/02841869109092419
  4. Gajalakshmi CK, Shanta V, Hakama M (1998). Risk factors for contralateral breast cancer in Chennai (Madras), India. Int J Epidemiol, 27, 743-50. https://doi.org/10.1093/ije/27.5.743
  5. Gilewski T, Ragupathi G, Bhuta S, Williams L, Musselli C (1998). Immunization of metastatic breast cancer patients with a fully synthetic globo-H conjugate: a phase I trial. PNAS, VOL?, 3270-5.
  6. Gajalakshmi V, Mathew A, Brennan P, et al (2009). Breastfeeding and breast cancer risk in India: A multicenter case-control study. Int J Cancer, 125, 662-5. https://doi.org/10.1002/ijc.24429
  7. Ibrahim NK, Murray J, Parker J, Finke L, Miles D (2004). Humoral immune responses to naturally occurring STn in metastatic breast cancer patients (MBC pts) treated with STn-KLH vaccine. Proceedings of the Am Society of Clinical Oncology, 23, 174.
  8. Mandana Ebrahimi M, Vahdaninia M, Ali Montazeri A (2011). Risk factors for breast cancer in Iran: a case-control study. Breast Cancer Research 2002, Vol 4 No 5. Available online http://breast-cancer- research.com/content/4/5/R10 (accessed on 1.1.2011)
  9. Parkin DM, Whelan SL, Ferlay J, Teppo L, Thomas DB, (2002). Cancer incidence in five continents, vol. VIII. IARC Sci Publ No. 155. Lyon: IARC, 2002.
  10. Rao DN, Ganesh B, Desai PB (1994). Role of reproductive factors in breast cancer in a low-risk area: a case-control study. Br J Cancer, 70, 129-32. https://doi.org/10.1038/bjc.1994.261
  11. Weir R, Day P, Ali W (2007). Risk factors for breast cancer in women A systematic review of the literature, NZHTA REPORT, 10, 69-71.
  12. Zheng T, Holford TR, Mayne ST, et al (2001). Lactation and breast cancer risk: a case-control study in Connecticut. Br J Cancer, 84, 1472-6. https://doi.org/10.1054/bjoc.2001.1793

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