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Elevated Level of Prostate Specific Antigen Among Prostate Cancer Patients and High Prevalence in the Gangetic Zone of Bihar, India

  • Nath, A. (Research Centre, Mahavir Cancer Sansthan) ;
  • Singh, J.K. (Research Centre, Mahavir Cancer Sansthan) ;
  • Vendan, S. Ezhil (Research Centre, Mahavir Cancer Sansthan) ;
  • Priyanka, Priyanka (Research Centre, Mahavir Cancer Sansthan) ;
  • Sinha, Shreya (Research Centre, Mahavir Cancer Sansthan)
  • 발행 : 2012.01.31

초록

Prostate cancer (CaP) is a common reproductive cancer among men. This study was conducted to correlate the cancer incidence with Gangetic zone and to correlate the tumor marker prostate specific antigen (PSA) level in serum with different age groups and stage of malignancy. Patients suffering from CaP in the pathology unit of Mahavir Cancer Sansthan (Hospital and Research Centre), Patna, Bihar, India were studied from June 2009 to May 2010. PSA level in the serum of CaP patients was estimated by ELISA method. CaP incidence was highly recorded in Gangetic zone than the non-Gangetic zone. Maximum patients were in the 56 - 75 years age group with a marked predominance. Results of PSA examination showed that serum PSA level was not correlating with the age of patient and stage of malignancy. Significantly, elevated level of more than 10 ng/ml of PSA was recorded among the studied cancer patients. In this study, it is concluded that Gangetic zone habitat have high risk of CaP and elevated level of PSA was marked in Bihar, India.

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참고문헌

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피인용 문헌

  1. Plasma Vascular Endothelial Growth Factors A and C in Patients undergoing Prostatic Biopsy and TURP for Suspected Prostatic Neoplasia vol.14, pp.3, 2013, https://doi.org/10.7314/APJCP.2013.14.3.2053
  2. Utility of Digital Rectal Examination, Serum Prostate Specific Antigen, and Transrectal Ultrasound in the Detection of Prostate Cancer: A Developing Country Perspective vol.15, pp.7, 2014, https://doi.org/10.7314/APJCP.2014.15.7.3087
  3. Clinical evaluation of prostate cancer gene 3 score in diagnosis among Chinese men with prostate cancer and benign prostatic hyperplasia vol.15, pp.1, 2015, https://doi.org/10.1186/s12894-015-0110-x