Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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Mandibular Reconstruction with Vascularized Osseous Free Flaps: a Review of the Literature

  • Kim, Bong-Chul (Department of Oral and Maxillofacial Surgery, Daejeon Dental Hospital, College of Dentistry, Wonkwang University) ;
  • Kim, So-Mi (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University, Korea College of Dentistry, Yonsei University) ;
  • Nam, Woong (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University, Korea College of Dentistry, Yonsei University) ;
  • Cha, In-Ho (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University, Korea College of Dentistry, Yonsei University) ;
  • Kim, Hyung-Jun (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University, Korea College of Dentistry, Yonsei University)
  • Published : 2012.02.29
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Abstract

Purpose: This article reviews a few of the commonly used types of vascularized osseous free flaps in maxillofacial reconstruction, which still represents the gold standard of restoration. We also discuss the developing concepts in maxillofacial reconstruction. Recent findings: Most of the literature reconfirms the established patterns of reconstruction with the aid of vascularized osseous free flaps. This method of free-tissue transfer is also feasible in cases of osteoradionecrosis or bisphosphonate-related osteonecrosis of the jaw. These flaps are also suitable for prosthetic restoration using osseointegrated dental implants. Summary: Vascularized osseous free flaps still remain the standard of care. Improvements upon the free-tissue transfer method employing vascularized osseous free flaps, such as distraction osteogenesis, tissue engineering, and imaging techniques, currently require further development, but these technologies could lead to improved outcomes of maxillofacial reconstruction in the near future.

Keywords

References

  1. AleAlam DS, Nuara M, Christian J (2009). Analysis of outcomes of vascularized flap reconstruction in patients with advanced mandibular osteoradionecrosis. Otolaryngol Head Neck Surg,141, 196-201. https://doi.org/10.1016/j.otohns.2009.03.013
  2. Allen MR, Burr DB (2009). The pathogenesis of bisphosphonaterelated osteonecrosis of the jaw: so many hypotheses, so few data. J Oral Maxillofac Surg, 67, 61- 70.
  3. Barber HD, Seckinger RJ, Hayden RE, et al (1995). Evaluation of osseointegration of endosseous implants in radiated, vascularized fibula flaps to the mandible: a pilot study. J Oral Maxillofac Surg, 53, 640-4. https://doi.org/10.1016/0278-2391(95)90158-2
  4. Bahr W, Stoll P, Wachter R (1998). Use of the ''double barrel'' free vascularized fibula in mandibular reconstruction. J Oral Maxillofac Surg, 56, 38-44. https://doi.org/10.1016/S0278-2391(98)90914-4
  5. Bamias A, Kastritis E, Bamia C, et al (2005). Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: incidence and risk factors. J Clin Oncol, 23, 8580-7. https://doi.org/10.1200/JCO.2005.02.8670
  6. Bell RB, Gregoire C (2009). Reconstruction of mandibular continuity defects using recombinant human bone morphogenetic protein 2: a note of caution in an atmosphere of exuberance. J Oral Maxillofac Surg, 67, 2673-8. https://doi.org/10.1016/j.joms.2009.07.085
  7. Blake F, Bubenheim M, Heiland M, et al (2008). Retrospective assessment of the peri-implant mucosa of implants inserted in reanastomosed or free bone grafts from the fibula or iliac crest. Int J Oral Maxillofac Implants, 23, 1102-8.
  8. Boyne PJ (1971). Transplantation, implantation and grafts. Dent Clin North Am, 15, 433-53.
  9. Brown J, Bekiroglu F, Shaw R (2010). Indications for the scapular flap in reconstructions of the head and neck. Br J Oral Maxillofac Surg, 48, 331-7. https://doi.org/10.1016/j.bjoms.2009.09.013
  10. Celik N, Wei FC, Chen HC, et al (2002). Osteoradionecrosis of the mandible after oromandibular cancer surgery. Plast Reconstr Surg, 109, 1875-81. https://doi.org/10.1097/00006534-200205000-00014
  11. Chang YM, Tsai CY, Wei FC (2008). One-stage, doublebarrel fibula osteoseptocutaneous flap and immediate dental implants for functional and aesthetic reconstruction of segmental mandibular defects. Plast Reconstr Surg, 122, 143-5. https://doi.org/10.1097/PRS.0b013e3181774135
  12. Daya M (2008). Peroneal artery perforator chimeric flap: changing the perspective in free fibula flap use in complex oromandibular reconstruction. J Reconstr Microsurg, 24, 413-8. https://doi.org/10.1055/s-0028-1082891
  13. Dodson TB (2009). Intravenous bisphosphonate therapy and bisphosphonate-related osteonecrosis of the jaws. J Oral Maxillofac Surg, 67, 44-52.
  14. Dufresne C, Cutting C, Valauri F, et al (1987). Reconstruction of mandibular and floor of mouth defects using the trapezius osteomyocutaneous flap. Plast Reconstr Surg, 79, 687-96. https://doi.org/10.1097/00006534-198705000-00001
  15. Engroff SL, Kim DD (2007). Treating bisphosphonate osteonecrosis of the jaws: is there a role for resection and vascularized reconstruction?. J Oral Maxillofac Surg, 65, 2374-85. https://doi.org/10.1016/j.joms.2006.07.012
  16. Ferrari S, Bianchi B, Savi A, et al (2008). Fibula free flap with endosseous implants for reconstructing a resected mandible in bisphosphonate osteonecrosis. J Oral Maxillofac Surg, 66, 999-1003. https://doi.org/10.1016/j.joms.2007.06.631
  17. Foster RD, Anthony JP, Sharma A, et al (1999). Vascularized bone flaps versus nonvascularized bone grafts for mandibular reconstruction: an outcome analysis of primary bone union and endosseous implant success. Head Neck, 21, 66-71. https://doi.org/10.1002/(SICI)1097-0347(199901)21:1<66::AID-HED9>3.0.CO;2-Z
  18. Franklin JD, Shack RB, Stone JD, et al (1980). Single-stage reconstruction of mandibular and soft tissue defects using a free osteocutaneous groin flap. Am J Surg, 140, 492-8. https://doi.org/10.1016/0002-9610(80)90198-1
  19. Garrett N, Roumanas ED, Blackwell KE, et al (2006). Efficacy of conventional and implant-supported mandibular resection prostheses: study overview and treatment outcomes. J Prosthet Dent, 96, 13-24. https://doi.org/10.1016/j.prosdent.2006.05.010
  20. Gellrich NC, Schramm A, Hammer B, et al (2002). Computer-assisted secondary reconstruction of unilateral posttraumatic orbital deformity. Plast Reconstr Surg, 110, 1417-29. https://doi.org/10.1097/00006534-200211000-00006
  21. Goldwaser BR, Chuang SK, Kaban LB, et al (2007). Risk factor assessment for the development of osteoradionecrosis. J Oral Maxillofac Surg, 65, 2311-6. https://doi.org/10.1016/j.joms.2007.05.021
  22. Granström G, Jacobsson M, Tjellstrom A (1992). Titanium implants in irradiated tissue: benefits from hyperbaric oxygen. Int J Oral Maxillofac Implants, 7, 15-25.
  23. Herford AS, Boyne PJ (2008). Reconstruction of mandibular continuity defects with bone morphogenetic protein-2 (rhBMP-2). J Oral Maxillofac Surg, 66, 616-24. https://doi.org/10.1016/j.joms.2007.11.021
  24. Hidalgo DA (1989). Fibula free flap: a new method of mandible reconstruction. Plast Reconstr Surg, 84, 71-9. https://doi.org/10.1097/00006534-198907000-00014
  25. Hidalgo DA, Pusic AL (2002). Free-flap mandibular reconstruction: a 10-year follow-up study. Plast Reconstr Surg, 110, 438-49. https://doi.org/10.1097/00006534-200208000-00010
  26. Hirsch DL, Bell RB, Dierks EJ, et al (2008). Analysis of microvascular free flaps for reconstruction of advanced mandibular osteoradionecrosis: a retrospective cohort study. J Oral Maxillofac Surg, 66, 2545-56. https://doi.org/10.1016/j.joms.2007.08.041
  27. Hou JS, Chen M, Pan CB, et al (2011). Immediate reconstruction of bilateral mandible defects: management based on computer-aided design/ computer-aided manufacturing rapid prototyping technology in combination with vascularized fibular osteomyocutaneous flap. J Oral Maxillofac Surg, 69, 1792-7. https://doi.org/10.1016/j.joms.2010.07.047
  28. Kang SH, Kim HJ, Cha IH, et al (2008). Mandibular condyle and infratemporal fossa reconstruction using vascularised iliac crest and vascularised calvarial bone graft. J Plast Reconstr Aesthet Surg, 61, 1561-2. https://doi.org/10.1016/j.bjps.2008.03.037
  29. Kim EK, Evangelista M, Evans GR (2008). Use of free tissue transfers in head and neck reconstruction. J Craniofac Surg, 19, 1577-82. https://doi.org/10.1097/SCS.0b013e3181897376
  30. Kimmel DB (2007). Mechanism of action, pharmacokinetic and pharmacodynamic profile, and clinical applications of nitrogen-containing bisphosphonates. J Dent Res, 86, 1022-33. https://doi.org/10.1177/154405910708601102
  31. Liu XJ, Gui L, Mao C, et al (2009). Applying computer techniques in maxillofacial reconstruction using a fibula flap: a messenger and an evaluation method. J Craniofac Surg, 20, 372-7. https://doi.org/10.1097/SCS.0b013e31819b9443
  32. Marx RE (1983). A new concept in the treatment of osteoradionecrosis. J Oral Maxillofac Surg, 41, 351-7. https://doi.org/10.1016/S0278-2391(83)80005-6
  33. Mucke T, Haarmann S, Wolff KD, et al (2009). Bisphosphonate related osteonecrosis of the jaws treated by surgical resection and immediate osseous microvascular reconstruction. J Craniomaxillofac Surg, 37, 291-7. https://doi.org/10.1016/j.jcms.2008.12.004
  34. Mucke T, Holzle F, Loeffelbein DJ, et al (2011). Maxillary reconstruction using microvascular free flaps. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 111, 51-7. https://doi.org/10.1016/j.tripleo.2010.03.042
  35. Nocini PF, Saia G, Bettini G, et al (2009). Vascularized fibula flap reconstruction of the mandible in bisphosphonate related osteonecrosis. Eur J Surg Oncol, 35, 373-9. https://doi.org/10.1016/j.ejso.2008.05.002
  36. O'Leary MJ, Martin PJ, Hayden RE (1994). The neurocutaneous free fibula flap in mandibular reconstruction. Otolaryngol Clin North Am, 27, 1081-96.
  37. Pogrel MA, Podlesh S, Anthony JP, et al (1997). A comparison of vascularized and nonvascularized bone grafts for reconstruction of mandibular continuity defects. J Oral Maxillofac Surg, 55, 1200-6. https://doi.org/10.1016/S0278-2391(97)90165-8
  38. Raoul G, Ruhin B, Briki S, et al (2009). Microsurgical reconstruction of the jaw with fibular grafts and implants. J Craniofac Surg, 20, 2105-17. https://doi.org/10.1097/SCS.0b013e3181bec611
  39. Ruggiero SL, Drew SJ (2007). Osteonecrosis of the jaws and bisphosphonate therapy. J Dent Res, 86, 1013-21. https://doi.org/10.1177/154405910708601101
  40. Ruggiero SL, Dodson TB, Assael LA, et al (2009). American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonaterelated osteonecrosis of the jaws- 2009 update. Aust Endod J, 35, 119-30. https://doi.org/10.1111/j.1747-4477.2009.00213.x
  41. Sacco AG, Chepeha DB (2007). Current status of transport-disc-distraction osteogenesis for mandibular reconstruction. Lancet Oncol, 8, 323-30. https://doi.org/10.1016/S1470-2045(07)70102-X
  42. Sakurai H, Takeuchi M, Fujiwara O, et al (2005). Total face reconstruction with one expanded free flap. Surg Technol Int, 14, 329-33.
  43. Salibian AH, Rappaport I, Allison G (1985). Functional oromandibular reconstruction with the microvascular composite groin flap. Plast Reconstr Surg, 76, 819-28.
  44. Salinas TJ, Desa VP, Katsnelson A, et al (2010). Clinical evaluation of implants in radiated fibula flaps. J Oral Maxillofac Surg, 68, 524-9. https://doi.org/10.1016/j.joms.2009.09.104
  45. Seth R, Futran ND, Alam DS, et al (2010). Outcomes of vascularized bone graft reconstruction of the mandible in bisphosphonate-related osteonecrosis of the jaws. Laryngoscope, 120, 2165-71. https://doi.org/10.1002/lary.21062
  46. Shpitzer T, Neligan PC, Gullane PJ, et al (1999). The free iliac crest and fibula flaps in vascularized oromandibular reconstruction: comparison and long-term evaluation. Head Neck, 21, 639-47. https://doi.org/10.1002/(SICI)1097-0347(199910)21:7<639::AID-HED8>3.0.CO;2-T
  47. Siemionow M, Unal S, Agaoglu G, et al (2006). A cadaver study in preparation for facial allograft transplantation in humans: part I. What are alternative sources for total facial defect coverage?. Plast Reconstr Surg, 117, 864-72. https://doi.org/10.1097/01.prs.0000204875.10333.56
  48. Swartz WM, Banis JC, Newton ED, et al (1986). The osteocutaneous scapular flap for mandibular and maxillary reconstruction. Plast Reconstr Surg, 77, 530-45. https://doi.org/10.1097/00006534-198604000-00003
  49. Taylor GI, Miller GD, Ham FJ (1975). The free vascularized bone graft: a clinical extension of microvascular techniques. Plast Reconstr Surg, 55, 533-44. https://doi.org/10.1097/00006534-197505000-00002
  50. Taylor GI, Townsend P, Corlett R (1979a). Superiority of the deep circumflex iliac vessels as the supply for free groin flaps. Plast Reconstr Surg, 64, 595-604. https://doi.org/10.1097/00006534-197964050-00001
  51. Taylor GI, Townsend P, Corlett R (1979b). Superiority of the deep circumflex iliac vessels as the supply for free groin flaps: clinical work. Plast Reconstr Surg, 64, 745-59. https://doi.org/10.1097/00006534-197912000-00001
  52. Valentini V, Agrillo A, Battisti A, et al (2005). Surgical planning in reconstruction of mandibular defect with fibula free flap: 15 patients. J Craniofac Surg, 16, 601-7. https://doi.org/10.1097/01.JPS.0000157811.06921.C5
  53. Wallace CG, Chang YM, Tsai CY, et al (2010). Harnessing the potential of the free fibula osteoseptocutaneous flap in mandible reconstruction. Plast Reconstr Surg, 125, 305-14. https://doi.org/10.1097/PRS.0b013e3181c2bb9d
  54. Wang KH, Inman JC, Hayden RE (2011). Modern concepts in mandibular reconstruction in oral and oropharyngeal cancer. Curr Opin Otolaryngol Head Neck Surg, 19, 119-24. https://doi.org/10.1097/MOO.0b013e328344a569

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