Asian Pacific Journal of Cancer Prevention

  • 제14권9호
  • /
  • Pages.5107-5110
  • /
  • 2013
  • /
  • 1513-7368(pISSN)
  • /
  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
권호 표지
DOI QR코드

DOI QR Code

Can Reproductive Characteristics Predict Bladder Cancer in Women with Haematuria?

  • Yavuzcan, Ali (Department of Obstetrics and Gynaecology, Duzce University Faculty of Medicine) ;
  • Caglar, Mete (Department of Obstetrics and Gynaecology, Duzce University Faculty of Medicine) ;
  • Kayikci, Muhammet Ali (Department of Urology, Duzce University Faculty of Medicine) ;
  • Basaran, Ekrem (Department of Urology, Duzce University Faculty of Medicine) ;
  • Tekin, Ali (Department of Urology, Duzce University Faculty of Medicine) ;
  • Ozdemir, Enver (Department of Urology, Duzce University Faculty of Medicine) ;
  • Dilbaz, Serdar (Department of Obstetrics and Gynaecology, Duzce University Faculty of Medicine) ;
  • Ustun, Yusuf (Department of Obstetrics and Gynaecology, Duzce University Faculty of Medicine) ;
  • Cam, Haydar Kamil (Department of Urology, Duzce University Faculty of Medicine)
  • 발행 : 2013.09.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Background: Among women with haematuria, defining individuals under high risk for bladder cancer based on reproductive factors prior to cystoscopy would be of great benefit in the management of this condition. The aim of this study was to compare age and reproductive factors such as menopausal status, parity, age at first delivery and age at the last delivery between women who have haematuria with or without bladder cancer. Materials and Methods: A total of 463 patients underwent diagnostic cystoscopy in D$\ddot{u}$zce University Faculty of Medicine between 1 June 2008 and 1 June 2013. Female patients who presented with persistent microscopic or macroscopic haematuria and underwent standard evaluation for haematuria including urinalysis, urine culture, urine cytology, urinary tract imaging with excretory urography or computerized tomography with contrast enhancement and endoscopic evaluation of the urethra and bladder were included in this study. Exclusion criteria were tobacco use and high risk occupations for bladder cancer such as textile, dry cleaning, painting and etc. Forteen women had hematuria due to benign conditions, and 18 due to bladder cancer. Data were retrospectively retrieved from the medical records of Duzce University Hospital. Results: Patients with haematuria due to benign reasons did not significantly differ from patients who were found to have bladder cancer in terms of age (p=0.28), menopausal status (p=0.29), mean parity (p=0.38), being nulliparous (p=0.57), parity ${\geq}3$ (p=0.22), age ${\leq}18$ years at first delivery (p=1.00), age ${\geq}30$ years at last delivery (p=0.26), age ${\geq}35$ years at last delivery (p=0.23) and percentage of the patients with advanced age (${\geq}65$ years) (p=0.18). Conclusions: It is difficult to predict a high risk for developing bladder cancer in women with haematuria based solely on reproductive factors.

키워드

참고문헌

  1. Aikawa K, Sugino T, Matsumoto S, et al (2003). The effect of ovariectomy and estradiol on rabbit bladder smooth muscle contraction and morphology. J Urol, 170, 634-7. https://doi.org/10.1097/01.ju.0000068723.05004.ca
  2. Aubertin-Leheudre M, Hamalainen E, Adlercreutz H (2011). Diets and hormonal levels in postmenopausal women with or without breast cancer. Nutr Cancer, 63, 514-24. https://doi.org/10.1080/01635581.2011.538487
  3. Badawi AF, Mostafa MH, Probert A, O'Connor PJ (1995). Role of schistosomiasis in human bladder cancer: evidence of association, aetiological factors, and basic mechanisms of carcinogenesis. Eur J Cancer Prev, 4, 45-59.
  4. Blakeman PJ, Hilton P, Bulmer JN (2000). Oestrogen and progesterone receptor expression in the female lower urinary tract, with reference to oestrogen status. BJU Int, 86, 32-8.
  5. Cantor KP, Lynch CF, Johnson D (1992). Bladder cancer, parity, and age at first birth. Cancer Causes Control, 3, 57-62. https://doi.org/10.1007/BF00051913
  6. Chamie K, Litwin MS, Bassett JC, et al (2013). Recurrence of high-risk bladder cancer: a population-based analysis. Cancer, 119, 3219-27. https://doi.org/10.1002/cncr.28147
  7. Coelingh Bennink HJ, Holinka CF, Diczfalusy E (2008). Estetrol review: profile and potential clinical applications. Climacteric, 11, 47-58. https://doi.org/10.1080/13697130802073425
  8. Davis-Dao CA, Henderson KD, Sullivan-Halley J, et al (2011). Lower risk in parous women suggests that hormonal factors are important in bladder cancer etiology. Cancer Epidemiol Biomarkers Prev, 20, 1156-70. https://doi.org/10.1158/1055-9965.EPI-11-0017
  9. Dietrich K, Demidenko E, Schned A, et al (2011). Parity, early menopause and the incidence of bladder cancer in women: a case-control study and meta-analysis. Eur J Cancer, 47, 592-9. https://doi.org/10.1016/j.ejca.2010.10.007
  10. Hextall A (2000). Oestrogens and lower urinary tract function. Maturitas, 36, 83-92. https://doi.org/10.1016/S0378-5122(00)00143-2
  11. Ho CC, Tan WP, Pathmanathan R, Tan WK, Tan HM (2013). Fluorescence-in situ-hybridization in the surveillance of urothelial cancers: can use of cystoscopy or ureteroscopy be deferred? Asian Pac Cancer Prev, 14, 4057-9. https://doi.org/10.7314/APJCP.2013.14.7.4057
  12. Huang AT, Kogevinas M, Silverman DT, et al (2009). Bladder cancer and reproductive factors among women in Spain. Cancer Causes Control, 20, 1907-13. https://doi.org/10.1007/s10552-009-9384-1
  13. Jemal A, Siegel R, Ward E, et al (2009). Cancer statistics, 2009. CA Cancer J Clin, 59, 225-49. https://doi.org/10.3322/caac.20006
  14. Khadra MH, Pickard RS, Charlton M, Powell PH, Neal DE (2000). A prospective analysis of 1,930 patients with hematuria to evaluate current diagnostic practice. J Urol, 163, 524-7. https://doi.org/10.1016/S0022-5347(05)67916-5
  15. Kobeissi LH, Yassine IA, Jabbour ME, Moussa MA, Dhaini HR (2013). Urinary bladder cancer risk factors: a Lebanese case- control study. Asian Pac Cancer Prev, 14, 3205-11. https://doi.org/10.7314/APJCP.2013.14.5.3205
  16. Krzeslak A, Jozwiak P, Formu E, et al (2012). Diagnostic value of glucose transporter 1 and 3 (GLUT1 and GLUT3) mRNA level in postmenopausal women with urinary bladder cancer. Przegląd Menopauzalny, 3, 178-82.
  17. McGrath M, Michaud DS, De Vivo I (2006). Hormonal and reproductive factors and the risk of bladder cancer in women. Am J Epidemiol, 163, 236-44. https://doi.org/10.1093/aje/kwj028
  18. Mishriki SF, Vint R, Somani BK (2012). Half of visible and half of recurrent visible hematuria cases have underlying pathology: prospective large cohort study with long-term follow up. J Urol, 187, 1561-5. https://doi.org/10.1016/j.juro.2011.12.100
  19. Nabi G, Greene D, O'Donnell MO (2004). Suspicious urinary cytology with negative evaluation for malignancy in the diagnostic investigation of haematuria: how to follow up? J Clin Pathol, 57, 365-8. https://doi.org/10.1136/jcp.2003.009696
  20. Prizment AE, Anderson KE, Harlow BL, Folsom AR (2007). Reproductive risk factors for incident bladder cancer: Iowa women's health study. Int J Cancer, 120, 1093-8.
  21. Rodriguez LV, Wang BY, Shortliffe LMD (2004). Structural changes in the bladder walls of pregnant and hormonetreated rats: correlation with bladder dynamics. BJU Int, 94, 1366-72. https://doi.org/10.1111/j.1464-410X.2004.05174.x
  22. Shariat SF, Sfakianos JP, Droller MJ, et al (2009). The effect of age and gender on bladder cancer: a critical review of the literature. BJU International, 105, 300-8.
  23. Shen SS, Smith CL, Hsieh JT, et al (2006). Expression of estrogen receptors-alpha and -beta in bladder cancer cell lines and human bladder tumor tissue. Cancer, 106, 2610-6. https://doi.org/10.1002/cncr.21945
  24. Srivastava AK, Singh PK, Srivastava K, et al (2013). Diagnostic role of survivin in urinary bladder cancer. Asian Pac Cancer Prev, 14, 81-5. https://doi.org/10.7314/APJCP.2013.14.1.81
  25. Wolpert BJ, Amr S, Ezzat S, et al (2010). Estrogen exposure and bladder cancer risk in Egyptian women. Maturitas, 67, 353-7. https://doi.org/10.1016/j.maturitas.2010.07.014

피인용 문헌

  1. External Validation of a Clinical Scoring System for Hematuria vol.15, pp.16, 2014, https://doi.org/10.7314/APJCP.2014.15.16.6819