참고문헌
- Chen J, Shao P, Cao Q, et al (2012). Genetic variations in a PTEN/AKT/mTOR axis and prostate cancer risk in a Chinese population. PLoS One, 7, e40817. https://doi.org/10.1371/journal.pone.0040817
- Choy E, Hornicek F, MacConaill L, et al (2012). Highthroughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes. Cancer, 118, 2905-14. https://doi.org/10.1002/cncr.26617
- Courtney KD, Corcoran RB, Engelman JA (2010). The PI3K pathway as drug target in human cancer. J Clin Oncol, 28, 1075-83. https://doi.org/10.1200/JCO.2009.25.3641
- Fendri A, Khabir A, Mnejja W, et al (2009). PIK3CA amplification is predictive of poor prognosis in Tunisian patients with nasopharyngeal carcinoma. Cancer Sci, 100, 2034-9. https://doi.org/10.1111/j.1349-7006.2009.01292.x
- Foster L, Dall GF, Reid R, et al (2007). Twentieth-century survival from osteosarcoma in childhood. Trends from 1933 to 2004. J Bone Joint Surg Br, 89, 1234-8.
- Fresno Vara JA, Casado E, de Castro J, et al (2004). PI3K/ Akt signalling pathway and cancer. Cancer Treat Rev, 30, 193-204. https://doi.org/10.1016/j.ctrv.2003.07.007
- Gorlick R (2009). Current concepts on the molecular biology of osteosarcoma. Cancer Treat Res, 152, 467-78. https://doi.org/10.1007/978-1-4419-0284-9_27
- Hameed M, Dorfman H (2011). Primary malignant bone tumors- -recent developments. Semin Diagn Pathol, 28, 86-101. https://doi.org/10.1053/j.semdp.2011.02.002
- Hildebrandt MA, Yang H, Hung MC, et al (2009). Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy. J Clin Oncol, 27, 857-71. https://doi.org/10.1200/JCO.2008.17.6297
- Jiang BH, Liu LZ (2009). PI3K/PTEN signaling in angiogenesis and tumorigenesis. Adv Cancer Res, 102, 19-65. https://doi.org/10.1016/S0065-230X(09)02002-8
- Linabery AM, Ross JA (2008). Trends in childhood cancer incidence in the U.S. (1992-2004). Cancer, 112, 416-32. https://doi.org/10.1002/cncr.23169
- Liu P, Cheng H, Roberts TM, et al (2009). Targeting the phosphoinositide 3-kinase pathway in cancer. Nat Rev Drug Discov, 8, 627-44. https://doi.org/10.1038/nrd2926
- Liu Y, Lv B, He Z, et al (2012). Lysyl oxidase polymorphisms and susceptibility to osteosarcoma. PLoS One, 7, e41610. https://doi.org/10.1371/journal.pone.0041610
- Liu Z, Hou P, Ji M, et al (2008). Highly prevalent genetic alterations in receptor tyrosine kinases and phosphatidylinositol 3-kinase/akt and mitogen-activated protein kinase pathways in anaplastic and follicular thyroid cancers. J Clin Endocrinol Metab, 93, 3106-16. https://doi.org/10.1210/jc.2008-0273
- Mure H, Matsuzaki K, Kitazato KT, et al (2010). Akt2 and Akt3 play a pivotal role in malignant gliomas. Neuro Oncol, 12, 221-32. https://doi.org/10.1093/neuonc/nop026
- Nakatani K, Thompson DA, Barthel A, et al (1999). Upregulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines. J Biol Chem, 274, 21528-32. https://doi.org/10.1074/jbc.274.31.21528
- Qian Y, Corum L, Meng Q, et al (2004). PI3K induced actin filament remodeling through Akt and p70S6K1: implication of essential role in cell migration. Am J Physiol Cell Physiol, 286, C153-63.
- Rosty C, Young JP, Walsh MD, et al (2013). PIK3CA activating mutation in colorectal carcinoma: associations with molecular features and survival. PLoS One, 8, e65479. https://doi.org/10.1371/journal.pone.0065479
- Samuels Y, Wang Z, Bardelli A, et al (2004). High frequency of mutations of the PIK3CA gene in human cancers. Science, 304, 554. https://doi.org/10.1126/science.1096502
- Savage SA, Mirabello L, Wang Z, et al (2013). Genome-wide association study identifies two susceptibility loci for osteosarcoma. Nat Genet, 45, 799-803. https://doi.org/10.1038/ng.2645
- Subbiah V, Kurzrock R (2011). Phase 1 clinical trials for sarcomas: the cutting edge. Curr Opin Oncol, 23, 352-60. https://doi.org/10.1097/CCO.0b013e3283477a94
- Sung JS, Park KH, Kim ST, et al (2012). Discovery and evaluation of polymorphisms in the AKT2 and AKT3 promoter regions for risk of Korean lung cancer. Genomics Inform, 10, 167-74. https://doi.org/10.5808/GI.2012.10.3.167
- Vivanco I, Sawyers CL (2002). The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer, 2, 489-501. https://doi.org/10.1038/nrc839
- Wang LE, Ma H, Hale KS, et al (2012). Roles of genetic variants in the PI3K and RAS/RAF pathways in susceptibility to endometrial cancer and clinical outcomes. J Cancer Res Clin Oncol, 138, 377-85. https://doi.org/10.1007/s00432-011-1103-0
- Xing JC, Tufano RP, Murugan AK, et al (2012). Single nucleotide polymorphism rs17849071 G/T in the PIK3CA gene is inversely associated with follicular thyroid cancer and PIK3CA amplification. PLoS One, 7, e49192. https://doi.org/10.1371/journal.pone.0049192
- Xing M (2010). Genetic alterations in the phosphatidylinositol-3 kinase/Akt pathway in thyroid cancer. Thyroid, 20, 697-706. https://doi.org/10.1089/thy.2010.1646
- Zhang L, Sun S, Zhou J, et al (2011). Knockdown of Akt1 promotes Akt2 upregulation and resistance to oxidativestress- induced apoptosis through control of multiple signaling pathways. Antioxid Redox Signal, 15, 1-17. https://doi.org/10.1089/ars.2010.3560
피인용 문헌
- Review of the Molecular Pathogenesis of Osteosarcoma vol.15, pp.15, 2014, https://doi.org/10.7314/APJCP.2014.15.15.5967
- Gemcitabine for the Treatment of Patients with Osteosarcoma vol.15, pp.17, 2014, https://doi.org/10.7314/APJCP.2014.15.17.7159
- Detection of PIK3CA Gene Mutations with HRM Analysis and Association with IGFBP-5 Expression Levels in Breast Cancer vol.15, pp.21, 2014, https://doi.org/10.7314/APJCP.2014.15.21.9327
- Clinicopathologic Features and Prognosis of Osteosarcoma in Turkish Adults vol.15, pp.8, 2014, https://doi.org/10.7314/APJCP.2014.15.8.3537
- GRM4 gene polymorphism is associated with susceptibility and prognosis of osteosarcoma in a Chinese Han population vol.31, pp.7, 2014, https://doi.org/10.1007/s12032-014-0050-4
- Polymorphisms in miRNA processing genes and their role in osteosarcoma risk vol.62, pp.5, 2015, https://doi.org/10.1002/pbc.25416
- Role of five small nucleotide polymorphisms in the VEGF gene on the susceptibility to osteosarcoma and overall survival of patients pp.1792-1082, 2015, https://doi.org/10.3892/ol.2015.3396
- RETRACTED ARTICLE: Common genetic variants in microRNA processing machinery genes are associated with risk and survival in patients with osteosarcoma vol.291, pp.1, 2016, https://doi.org/10.1007/s00438-015-1006-x
- MicroRNA-26a induces osteosarcoma cell growth and metastasis via the Wnt/β-catenin pathway vol.11, pp.2, 2015, https://doi.org/10.3892/ol.2015.4073