동의생리병리학회지 (Journal of Physiology & Pathology in Korean Medicine)

  • 제27권1호
  • /
  • Pages.107-111
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  • 2013
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  • 1738-7698(pISSN)
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  • 2288-2529(eISSN)
대한동의생리학회·한의병리학회 ( The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine)
권호 표지

프로바이오틱스 함유 한방소화제의 제조 및 특성

Production and Characterization of Herbal Digestive Medicine Containing Probiotics

  • 최학주 (대전대학교 난치성면역질환 동서생명의학연구센터) ;
  • 김동희 (대전대학교 난치성면역질환 동서생명의학연구센터) ;
  • 지중구 (중부대학교 한방건강관리학과) ;
  • 미야모토 (큐슈대학교 약학연구원 천연물화학연구실) ;
  • 신광수 (대전대학교 자연과학대학 미생물생명공학과)
  • Choi, Hak Joo (Traditional and Biomedical Research Center, Daejeon University) ;
  • Kim, Dong Hee (Traditional and Biomedical Research Center, Daejeon University) ;
  • Ji, Joong Gu (Department of Oriental Health Care, Joongbu University) ;
  • Miyamoto, Tomofumi (Department of Chemo-Pharmaceutical Science, Faculty of Pharmaceutical Sciences, Kyusu University) ;
  • Shin, Kwang Soo (Department of Microbiology & Biotechnology, College of Natural Sciences, Daejeon University)
  • 투고 : 2013.01.07
  • 심사 : 2013.02.20
  • 발행 : 2013.02.25
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초록

To investigate the possible usage as probiotics, we isolated and identified one strain of bacillus from Korean traditional food, Jeotgal. The isolate was identified as Bacillus megaterium KS12 by examining its biochemical properties and 16S rRNA sequence analysis (99% similarity). B. megaterium KS12 exhibited high viability in artificial gastric juice for 3 h and in artificial bile salts for 24 h, about 14.4 and 14%, respectively. The herbal digestive medicine containing the isolate showed high starch hydrolytic activity and proteolytic activities (about 6-fold) compared to traditional herbal digestive medicine. The viable cells in the herbal digestive medicine containing the isolate were higher than those of traditional herbal digestive medicine.

키워드

참고문헌

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