DOI QR코드

DOI QR Code

Intrathecal Meperidine Plus Lidocaine for Prevention of Shivering during Cesarean Section

  • 투고 : 2013.08.05
  • 심사 : 2013.09.25
  • 발행 : 2013.10.01

초록

Background: Shivering related to spinal anesthesia may interfere with monitoring and is uncomfortable. The aim of the present study was to investigate low-dose intrathecal meperidine for the prevention of shivering after induction of spinal anesthesia in parturients with cesarean section. Methods: This was a prospective randomized, double-blind, placebo-controlled trial including 100 parturients, of American Society of Anesthesiologists (ASA) physical status I or II, scheduled for elective cesarean section under spinal anesthesia who were randomly assigned to a meperidine (0.2 mg/kg) plus hyperbaric lidocaine (5%, 75 mg, n = 50; group M) group or a placebo plus hyperbaric lidocaine (5%, 75 mg, n = 50; group L) group. Demographic and surgical data, adverse events, and the mean intensity for each parturient were assessed during the entire study period by a blinded observer. Results: There were no significant differences between the two study groups regarding the demographic and surgical data (P > 0.05). The incidence of shivering during the entire study period significantly decreased in the group of parturients who received intrathecal meperidine (P = 0.04). There were no significant differences in nausea and vomiting between the two groups. Conclusions: Low-dose intrathecal meperidine (10 mg) is safe and effective in reducing the incidence and severity of shivering associated with spinal anesthesia in parturients with cesarean section.

키워드

참고문헌

  1. Ciofolo MJ, Clergue F, Devilliers C, Ben Ammar M, Viars P. Changes in ventilation, oxygen uptake, and carbon dioxide output during recovery from isoflurane anesthesia. Anesthesiology 1989; 70: 737-41. https://doi.org/10.1097/00000542-198905000-00004
  2. Kurz A, Sessler DI, Schroeder M, Kurz M. Thermoregulatory response thresholds during spinal anesthesia. Anesth Analg 1993; 77: 721-6.
  3. Han SY, Jin HC, Yang WD, Lee JH, Cho SH, Chae WS, et al. The effect of low-dose ketamine on post-caesarean delivery analgesia after spinal anesthesia. Korean J Pain 2013; 26: 270-6. https://doi.org/10.3344/kjp.2013.26.3.270
  4. Matsukawa T, Sessler DI, Christensen R, Ozaki M, Schroeder M. Heat flow and distribution during epidural anesthesia. Anesthesiology 1995; 83: 961-7. https://doi.org/10.1097/00000542-199511000-00008
  5. Lee C, Choi DH, Chae SU. Circadian effects on neural blockade of intrathecal hyperbaric bupivacaine. Korean J Pain 2010; 23: 186-9. https://doi.org/10.3344/kjp.2010.23.3.186
  6. Crowley LJ, Buggy DJ. Shivering and neuraxial anesthesia. Reg Anesth Pain Med 2008; 33: 241-52. https://doi.org/10.1097/00115550-200805000-00009
  7. Han JW, Kang HS, Choi SK, Park SJ, Park HJ, Lim TH. Comparison of the effects of intrathecal fentanyl and meperidine on shivering after cesarean delivery under spinal anesthesia. Korean J Anesthesiol 2007; 52: 657-62. https://doi.org/10.4097/kjae.2007.52.6.657
  8. Alfonsi P, Hongnat JM, Lebrault C, Chauvin M. The effects of pethidine, fentanyl and lignocaine on postanaesthetic shivering. Anaesthesia 1995; 50: 214-7. https://doi.org/10.1111/j.1365-2044.1995.tb04559.x
  9. Alfonsi P, Sessler DI, Du Manoir B, Levron JC, Le Moing JP, Chauvin M. The effects of meperidine and sufentanil on the shivering threshold in postoperative patients. Anesthesiology 1998; 89: 43-8. https://doi.org/10.1097/00000542-199807000-00009
  10. Kurz M, Belani KG, Sessler DI, Kurz A, Larson MD, Schroeder M, et al. Naloxone, meperidine, and shivering. Anesthesiology 1993; 79: 1193-201. https://doi.org/10.1097/00000542-199312000-00009
  11. Delaunay L, Bonnet F, Liu N, Beydon L, Catoire P, Sessler DI. Clonidine comparably decreases the thermoregulatory thresholds for vasoconstriction and shivering in humans. Anesthesiology 1993; 79: 470-4. https://doi.org/10.1097/00000542-199309000-00009
  12. Fukuda K. Intravenous opioid anesthetics. In: Miller's anesthesia. 6th ed. Edited by Miller RD. New York (NY), Elsevier Churchill Livingstone. 2005, pp 379-438.
  13. Casey WF, Smith CE, Katz JM, O'Loughlin K, Weeks SK. Intravenous meperidine for control of shivering during caesarean section under epidural anaesthesia. Can J Anaesth 1988; 35: 128-33. https://doi.org/10.1007/BF03010651
  14. Chen JC, Hsu SW, Hu LH, Hong YJ, Tsai PS, Lin TC, et al. Intrathecal meperidine attenuates shivering induced by spinal anesthesia. Ma Zui Xue Za Zhi 1993; 31: 19-24.
  15. Roy JD, Girard M, Drolet P. Intrathecal meperidine decreases shivering during cesarean delivery under spinal anesthesia. Anesth Analg 2004; 98: 230-4.
  16. Hong JY, Lee IH. Comparison of the effects of intrathecal morphine and pethidine on shivering after Caesarean delivery under combined-spinal epidural anaesthesia. Anaesthesia 2005; 60: 1168-72. https://doi.org/10.1111/j.1365-2044.2005.04158.x
  17. Khan ZH, Zanjani AP, Makarem J, Samadi S. Antishivering effects of two different doses of intrathecal meperidine in caesarean section: a prospective randomised blinded study. Eur J Anaesthesiol 2011; 28: 202-6.
  18. Crossley AW, Mahajan RP. The intensity of postoperative shivering is unrelated to axillary temperature. Anaesthesia 1994; 49: 205-7.
  19. Horn EP, Schroeder F, Wilhelm S, Sessler DI, Standl T, von dem Busche K, et al. Postoperative pain facilitates nonthermoregulatory tremor. Anesthesiology 1999; 91: 979-84. https://doi.org/10.1097/00000542-199910000-00017
  20. Mahajan RP, Grover VK, Sharma SL, Singh H. Intraocular pressure changes during muscular hyperactivity after general anesthesia. Anesthesiology 1987; 66: 419-21. https://doi.org/10.1097/00000542-198703000-00030
  21. de Courcy JG. Artefactual 'hypotension' from shivering. Anaesthesia 1989; 44: 787-8.
  22. Barker SJ, Shah NK. The effects of motion on the performance of pulse oximeters in volunteers (revised publication). Anesthesiology 1997; 86: 101-8. https://doi.org/10.1097/00000542-199701000-00014
  23. Just B, Delva E, Camus Y, Lienhart A. Oxygen uptake during recovery following naloxone. Relationship with intraoperative heat loss. Anesthesiology 1992; 76: 60-4. https://doi.org/10.1097/00000542-199201000-00009
  24. Jones HD, McLaren CA. Posoperative shvering and hypoxaemia after halothane, nitrous oxide and oxygen anaesthesia. Br J Anaesth 1965; 37: 35-41. https://doi.org/10.1093/bja/37.1.35
  25. Pflug AE, Aasheim GM, Foster C, Martin RW. Prevention of post-anaesthesia shivering. Can Anaesth Soc J 1978; 25: 43-9. https://doi.org/10.1007/BF03006783
  26. Entezari Asl M, Isazadehfar K, Akhavanakbari G, Khoshbaten M. The effect of ondansetron in prevention of postoperative shivering after general anesthesia in gynecological surgery. Iran Red Crescent Med J 2012; 14: 316-7.
  27. Shoar S, Esmaeili S, Khorgami Z, Naderan M, Shoar N. Efficacy of acupuncture in prevention of postoperative anaesthesia-related shivering. Acupunct Med 2013; 31: 120-1. https://doi.org/10.1136/acupmed-2012-010250
  28. Horn EP, Werner C, Sessler DI, Steinfath M, Schulte am Esch J. Late intraoperative clonidine administration prevents postanesthetic shivering after total intravenous or volatile anesthesia. Anesth Analg 1997; 84: 613-7.
  29. Stoelting RK, Hillier SC. Pharmacology & physiology in anesthetic practice. 4th ed. Philadelphia (PA), Lippincott Williams & Wilkins. 2006, p 864.
  30. Kurz A, Ikeda T, Sessler DI, Larson MD, Bjorksten AR, Dechert M, et al. Meperidine decreases the shivering threshold twice as much as the vasoconstriction threshold. Anesthesiology 1997; 86: 1046-54. https://doi.org/10.1097/00000542-199705000-00007

피인용 문헌

  1. The Preventive Role of Low-Dose Intravenous Ketamine on Postoperative Shivering in Children: A Placebo Randomized Controlled Trial vol.In Press, pp.In Press, 2016, https://doi.org/10.5812/aapm.32172
  2. Comparison of the Effects of Intrathecal Meperidine and Morphine on Incidence and Intensity of Shivering After Caesarean Sections Under Spinal Anesthesia: A Randomized Controlled Trial vol.19, pp.7, 2017, https://doi.org/10.5812/ircmj.55567
  3. Intrathecal Sufentanil Does Not Reduce Shivering During Neuraxial Anesthesia: A Meta-Analysis vol.22, pp.None, 2016, https://doi.org/10.12659/msm.897293
  4. Effect of low dose of intrathecal pethidine on the incidence and intensity of shivering during cesarean section under spinal anesthesia: a randomized, placebo-controlled, double-blind clinical trial vol.10, pp.None, 2016, https://doi.org/10.2147/dddt.s115201
  5. Preventing shivering with adjuvant low dose intrathecal meperidine: A meta-analysis of randomized controlled trials with trial sequential analysis vol.7, pp.None, 2013, https://doi.org/10.1038/s41598-017-14917-5
  6. Intrathecal Tramadol for Prevention of Postanesthesia Shivering after Subarachnoid Block: A Prospective Randomized Placebo-Controlled Comparison of Two Different Doses (10 and 20 mg) vol.12, pp.2, 2013, https://doi.org/10.4103/aer.aer_75_18
  7. Shivering prevention and treatment during cesarean delivery under neuraxial anesthesia: a systematic review vol.84, pp.12, 2018, https://doi.org/10.23736/s0375-9393.18.12478-3
  8. Neuraxial adjuvants for prevention of perioperative shivering during cesarean section: A network meta-analysis following the PRISMA guidelines vol.7, pp.16, 2019, https://doi.org/10.12998/wjcc.v7.i16.2287
  9. The Effect of Intrathecal Meperidine on Maternal and Newborn Outcomes After Cesarean Section: A Systematic Review and Meta-Analysis Study vol.10, pp.2, 2013, https://doi.org/10.5812/aapm.100375
  10. Effect of intrathecal lipophilic opioids on the incidence of shivering in women undergoing cesarean delivery after spinal anesthesia: a systematic review and bayesian network meta- analysis of randomi vol.20, pp.1, 2013, https://doi.org/10.1186/s12871-020-01116-5