Asian Pacific Journal of Cancer Prevention

  • 제15권1호
  • /
  • Pages.11-16
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  • 2014
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  • 1513-7368(pISSN)
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  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
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FOXA1: a Promising Prognostic Marker in Breast Cancer

  • Hu, Qing (Department of General Surgery, Xuzhou Medical College) ;
  • Luo, Zhou (Department of Oncology, Nanjing Medical University) ;
  • Xu, Tao (Department of Oncology, Nanjing Medical University) ;
  • Zhang, Jun-Ying (Department of Oncology, Xuzhou Medical College) ;
  • Zhu, Ying (Department of Oncology, Nanjing Medical University) ;
  • Chen, Wei-Xian (Department of Oncology, Nanjing Medical University) ;
  • Zhong, Shan-Liang (Clinical Laboratory Center) ;
  • Zhao, Jian-Hua (Clinical Laboratory Center) ;
  • Tang, Jin-Hai (Department of General Surgery, Jiangsu Cancer Hospital)
  • 발행 : 2014.01.15
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초록

Accurate diagnosis and proper monitoring of cancer patients remain important obstacles for successful cancer treatment. The search for cancer biomarkers can aid in more accurate prediction of clinical outcome and may also reveal novel predictive factors and therapeutic targets. One such prognostic marker seems to be FOXA1. Many studies have shown that FOXA1 is strongly expressed in a vast majority of cancers, including breast cancer, in which high expression is associated with a good prognosis. In this review, we summarize the role of this transcription factor in the development and prognosis of breast cancer in the hope of providing insights into utility of FOXA1 as a novel biomarker.

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참고문헌

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