Asian Pacific Journal of Cancer Prevention

  • 제15권7호
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  • Pages.3239-3245
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  • 2014
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  • 1513-7368(pISSN)
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  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
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Human Papillomavirus Vaccine Awareness, Acceptability, and Decision-Making Factors among Chinese College Students

  • Wang, Shao-Ming (Cancer Institute/ Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College) ;
  • Zhang, Shao-Kai (Cancer Institute/ Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College) ;
  • Pan, Xiong-Fei (Cancer Institute/ Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College) ;
  • Ren, Ze-Fang (Department of Epidemiology and Biostatistics, School of Public Health, Sun Yat-sen University) ;
  • Yang, Chun-Xia (Department of Epidemiology, West China School of Public Health, Sichuan University) ;
  • Wang, Zeng-Zhen (Department of Epidemiology and Health Statistics, School of Public Health, Tongji Medical College of Huazhong University of Science and Technology) ;
  • Gao, Xiao-Hong (Department of Epidemiology, School of Public Health, Dalian Medical University) ;
  • Li, Man (School of Public Health, Capital Medical University) ;
  • Zheng, Quan-Qing (Department of Public Health, Medical School of Xi'an Jiaotong University) ;
  • Ma, Wei (Department of Epidemiology and Health Statistics, School of Public Health, Shandong University) ;
  • Zhao, Fang-Hui (Cancer Institute/ Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College) ;
  • Qiao, You-Lin (Cancer Institute/ Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College) ;
  • Sivasubramaniam, Priya (Cancer Institute/ Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College)
  • 발행 : 2014.04.01
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초록

Background: College students are recommended as the target groups for catch-up human papillomavirus (HPV) vaccination. Systematical exploration of awareness, acceptability, and decision-making factors of HPV vaccination among Chinese college students has been limited. Materials and Methods: A multi-center survey was conducted in mainland China between November 2011 and May 2012. College students aged 18-22 years were stratified by their grade, gender, and major for sampling. Socio-demographic and HPV-related information such as knowledge, perceptions, acceptability, and attitudes were collected through a questionnaire. Results: A total of 3,497 undergraduates completed the questionnaire, among which 1,686 were males. The acceptability of the HPV vaccine was high (70.8%). Undergraduates from high-level universities, at lower grade, or with greater prior knowledge of HPV vaccines showed higher acceptability of HPV vaccination ($p_{trend}$ <0.001). Additionally, undergraduates with vaccination experience outside the National Expanded Program on Immunization (OR=1.29; 95%CI: 1.10-1.51) or fear of HPV-related diseases (OR=2.79; 95%CI: 2.28-3.41) were more willing to accept HPV vaccination. General knowledge of HPV vaccine was low among undergraduates, and safety was a major concern (71.05%). The majority of students wished to pay less than 300RMB for HPV vaccine and chose the Chinese Center for Disease Control and Prevention as the most appropriate venue for vaccination. Conclusions: Although most undergraduates demonstrate positive attitudes towards HPV vaccination, challenges pertaining to introduction exist in China. Corresponding proactive education and governmental subsidy to do so are urgently needed by this age-group population. Suggestions and potential strategies indicated may help shape the future HPV vaccination program in China.

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참고문헌

  1. Allen JD, Fantasia HC, Fontenot H, et al (2009). College men's knowledge, attitudes, and beliefs about the human papillomavirus infection and vaccine. J Adolesc Health, 45, 535-7. https://doi.org/10.1016/j.jadohealth.2009.05.014
  2. Canfell K, Shi JF, Lew JB, et al (2011). Prevention of cervical cancer in rural China: evaluation of HPV vaccination and primary HPV screening strategies. Vaccine, 29, 2487-94. https://doi.org/10.1016/j.vaccine.2010.12.085
  3. Ferlay J SI, Ervik M, Dikshit R, et al (2013). GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet]. Lyon, France: International Agency for Research on Cancer; 2013.
  4. Garland SM, Hernandez-Avila M, Wheeler CM, et al (2007). Quadrivalent vaccine against human papillomavirus to prevent anogenital diseases. N Engl J Med, 356, 1928-43. https://doi.org/10.1056/NEJMoa061760
  5. Harper DM (2008). Impact of vaccination with Cervarix (trade mark) on subsequent HPV-16/18 infection and cervical disease in women 15-25 years of age. Gynecol Oncol, 110, 11-7.
  6. Jones M, Cook R (2008). Intent to receive an HPV vaccine among university men and women and implications for vaccine administration. J Am Coll Health, 57, 23-32. https://doi.org/10.3200/JACH.57.1.23-32
  7. Kang HS, Moneyham L (2009). Attitudes toward and intention to receive the human papilloma virus (HPV) vaccination and intention to use condoms among female Korean college students. Vaccine, 28, 811-6.
  8. Katz ML, Krieger JL, Roberto AJ (2011). Human papillomavirus (HPV): college male's knowledge, perceived risk, sources of information, vaccine barriers and communication. J Mens health, 8, 175-84. https://doi.org/10.1016/j.jomh.2011.04.002
  9. Kreimer AR, Rodriguez AC, Hildesheim A, et al (2011). Proof-of-principle evaluation of the efficacy of fewer than three doses of a bivalent HPV16/18 vaccine. J Natl Cancer Inst, 103, 1444-51. https://doi.org/10.1093/jnci/djr319
  10. Li J, Li LK, Ma JF, et al (2009). Knowledge and attitudes about human papillomavirus (HPV) and HPV vaccines among women living in metropolitan and rural regions of China. Vaccine, 27, 1210-5. https://doi.org/10.1016/j.vaccine.2008.12.020
  11. Li R, Li Y, Radley D, et al (2012). Safety and immunogenicity of a vaccine targeting human papillomavirus types 6, 11, 16 and 18: a randomized, double-blind, placebo-controlled trial in Chinese males and females. Vaccine, 30, 4284-91. https://doi.org/10.1016/j.vaccine.2012.02.079
  12. Liddon N, Hood J, Wynn BA, et al (2010). Acceptability of human papillomavirus vaccine for males: a review of the literature. J Adolesc Health, 46, 113-23. https://doi.org/10.1016/j.jadohealth.2009.11.199
  13. Lindley LL, Elkind JS, Landi SN, et al (2013). Receipt of the human papillomavirus vaccine among female college students in the United States, 2009. J Am Coll Health, 61, 18-27. https://doi.org/10.1080/07448481.2012.750607
  14. Makwe CC, Anorlu RI, Odeyemi KA (2012). Human papillomavirus (HPV) infection and vaccines: knowledge, attitude and perception among female students at the University of Lagos, Lagos, Nigeria. J Epidemiol Glob Health, 2, 199-206. https://doi.org/10.1016/j.jegh.2012.11.001
  15. Marek E, Dergez T, Kricskovics A, et al (2011). Difficulties in the prevention of cervical cancer: adults' attitudes towards HPV vaccination 3 years after introducing the vaccine in Hungary. Vaccine, 29, 5122-9. https://doi.org/10.1016/j.vaccine.2011.05.048
  16. Markowitz LE, Tsu V, Deeks SL, et al (2012). Human papillomavirus vaccine introduction-the first five years. Vaccine, 30, 139-48. https://doi.org/10.1016/j.vaccine.2012.05.039
  17. Wang SM, Qiao YL (2010). Perspective of implementation of prophylactic HPV vaccine in China, Oncology Progress, 3, 134-8.
  18. WHO (2009). Human papillomavirus vaccines: WHO position paper. Biologicals, 37, 338-44. https://doi.org/10.1016/j.biologicals.2009.04.005
  19. Zhang SK, Pan XF, Wang SM, et al (2013). Perceptions and acceptability of HPV vaccination among parents of young adolescents: A multicenter national survey in China. Vaccine, 31, 3244-9. https://doi.org/10.1016/j.vaccine.2013.05.046
  20. Zhao FH, Tiggelaar SM, Hu SY, et al (2012a). A multi-center survey of age of sexual debut and sexual behavior in Chinese women: suggestions for optimal age of human papillomavirus vaccination in China. Cancer Epidemiol, 36, 384-90. https://doi.org/10.1016/j.canep.2012.01.009
  21. Zhao FH, Tiggelaar SM, Hu SY, et al (2012b). A multi-center survey of HPV knowledge and attitudes toward HPV vaccination among women, government officials, and medical personnel in China. Asian Pac J Cancer Prev, 13, 2369-78. https://doi.org/10.7314/APJCP.2012.13.5.2369

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  4. Estimating long-term clinical effectiveness and cost-effectiveness of HPV 16/18 vaccine in China vol.16, pp.1, 2016, https://doi.org/10.1186/s12885-016-2893-x
  5. Attitude, Acceptability and Knowledge of HPV Vaccination among Local University Students in Hong Kong vol.13, pp.5, 2016, https://doi.org/10.3390/ijerph13050486