Asian Pacific Journal of Cancer Prevention

  • 제15권13호
  • /
  • Pages.5423-5425
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  • 2014
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  • 1513-7368(pISSN)
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  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
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Risk Factors for Endometrial Hyperplasia Concomitant Endometrial Polyps in Pre- and Post-menopausal Women

  • Topcu, Hasan Onur (Obstetrics and Gynecology, Medicine, Dr Zekai Tahir Burak Women's Health Education and Research Hospital) ;
  • Erkaya, Salim (Obstetrics and Gynecology, Medicine, Dr Zekai Tahir Burak Women's Health Education and Research Hospital) ;
  • Guzel, Ali Irfan (Obstetrics and Gynecology, Medicine, Dr Zekai Tahir Burak Women's Health Education and Research Hospital) ;
  • Kokanali, Mahmut Kuntay (Obstetrics and Gynecology, Medicine, Dr Zekai Tahir Burak Women's Health Education and Research Hospital) ;
  • Sarıkaya, Esma (Obstetrics and Gynecology, Medicine, Dr Zekai Tahir Burak Women's Health Education and Research Hospital) ;
  • Muftuoglu, Kamil Hakan (Department of Pathology Dr Zekai Tahir Burak Women's Health Education and Research Hospital) ;
  • Doganay, Melike (Obstetrics and Gynecology, Medicine, Dr Zekai Tahir Burak Women's Health Education and Research Hospital)
  • 발행 : 2014.07.15
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초록

Purpose: To evaluate the risk factors for endometrial hyperplasia concomitant endometrial polyps in pre- and post-menopausal women. Materials and Methods: A total of 203 patients undergoing endometrial sampling before hysterectomy were evaluated in this retrospective study. Data recorded were age, gravidity, parity, body mass index (BMI: weight(kg)/$height(m)^2$), endometrial thickness (ET), menopausal status, presence of adenomyosis and diabetes mellitus. Results: Endometrial hyperplasia and polyps were detected in 13 patients. There were statistically significant differences in terms of age, menopausal status, morbid obesity and diabetes mellitus (p<0.005). Logistic regression demonstrated that menopausal status and presence of diabetes mellitus were independent risk factors. Conclusions: According to the current study; menopause and diabetes mellitus are strong risk factors for the presence of concomitant endometrial polyps and endometrial hyperplasia.

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참고문헌

  1. Acmaz G, Aksoy H, Albayrak E, et al (2014). Evaluation of endometrial precancerous lesions in postmenopausal obese women-a high riskgroup? Asian Pac J Cancer Prev, 15, 195-198. https://doi.org/10.7314/APJCP.2014.15.1.195
  2. Balik G, Kagitci M, Ustuner I, et al (2013). Which endometrial pathologies need intraoperative frozen sections? Asian Pac J Cancer Prev, 14, 6121-6125. https://doi.org/10.7314/APJCP.2013.14.10.6121
  3. Costa-Paiva L, Godoy CE Jr, Antunes A Jr, et al (2011). Risk of malignancy in endometrial polyps in premenopausal andpostmenopausal women according to clinicopathologic characteristics. Menopause, 18, 1278-82. https://doi.org/10.1097/gme.0b013e31821e23a1
  4. de Carvalho S, Campaner AB, Lima SM, et al (2011). Differential expression of estrogen and progesterone receptors in endometrial polyps andadjacent endometrium in postmenopausal women. Anal Quant Cytol Histol, 33, 61-67.
  5. Hileeto D, Fadare O, Martel M, et al (2005). Age dependent association of endometrial polyps with increased risk of cancer involvement. World J Surg Oncol, 9, 8.
  6. Giordano G, Gnetti L, Merisio C, et al (2007). Postmenopausal status, hypertension and obesity as risk factors for malignant transformationin endometrial polyps. Maturitas, 20, 190-7.
  7. Karimi Zarchi M, Behtash N, Sekhavat L, et al (2009). Effects of tamoxifen on the cervix and uterus in women with breast cancer: experience with Iranian patients and a literature review. Asian Pac J Cancer Prev, 10, 595-8.
  8. Kim MK, Seong SJ (2013). LNG-IUS treatment of non-atypical endometrial hyperplasia: Can Pipelle endometrial samplingbe an accurate method of follow-up evaluation? J Gynecol Oncol, 24, 103-4. https://doi.org/10.3802/jgo.2013.24.2.103
  9. Kleebkaow P, Maneetab S, Somboonporn W, et al (2008). Preoperative and postoperative agreement of histopathological findings incases of endometrial hyperplasia. Asian Pac J Cancer Prev, 9, 89-91.
  10. Lenci MA, do Nascimento VA, Grandini AB, et al (2014). Premalignant and malignant lesions in endometrial polyps in patients undergoing hysteroscopic polypectomy. Einstein (Sao Paulo), 12, 16-21. https://doi.org/10.1590/S1679-45082014AO2764
  11. Li XC, Song WJ (2013). Endometrial intraepithelial neoplasia (EIN) in endometrial biopsy specimens categorized by the1994 World Health Organization classification for endometrial hyperplasia. Asian Pac J Cancer Prev, 14, 5935-9. https://doi.org/10.7314/APJCP.2013.14.10.5935
  12. Munro MG, Critchley HO, Broder MS, et al (2011). FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age. Int J Gynaecol Obstet, 113, 3-13. https://doi.org/10.1016/j.ijgo.2010.11.011
  13. Nicholson WK, Ellison SA, Grason H, et al (2001). Patterns of ambulatory care use for gynecologic conditions: A national study. Am J Obstet Gynecol, 184, 523-530 https://doi.org/10.1067/mob.2001.111795
  14. Salim S, Won H, Nesbitt-Hawes E, et al (2011). Diagnosis and management of endometrial polyps: a critical review of the literature. J Minim Invasive Gynecol, 18, 569-81. https://doi.org/10.1016/j.jmig.2011.05.018

피인용 문헌

  1. Systemic hypertension and diabetes mellitus as predictors of malignancy among women with endometrial polyps vol.23, pp.6, 2016, https://doi.org/10.1097/GME.0000000000000602