The Korean Journal of Physiology and Pharmacology

The Korean Society of Pharmacology (대한약리학회)
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Low Intensity Resistance Exercise Training with Blood Flow Restriction: Insight into Cardiovascular Function, and Skeletal Muscle Hypertrophy in Humans

  • Park, Song-Young (Geriatric Research, Education, and Clinical Center, George E. Whalen VA Medical Center) ;
  • Kwak, Yi Sub (Department of Physical Education, Dong-Eui University) ;
  • Harveson, Andrew (Department of Exercise and Sport Science, University of Utah, Salt Lake City) ;
  • Weavil, Joshua C. (Geriatric Research, Education, and Clinical Center, George E. Whalen VA Medical Center) ;
  • Seo, Kook E. (Department of Sports Science, Pusan National University)
  • Received : 2015.02.12
  • Accepted : 2015.04.07
  • Published : 2015.05.01
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Abstract

Attenuated functional exercise capacity in elderly and diseased populations is a common problem, and stems primarily from physical inactivity. Decreased function and exercise capacity can be restored by maintaining muscular strength and mass, which are key factors in an independent and healthy life. Resistance exercise has been used to prevent muscle loss and improve muscular strength and mass. However, the intensities necessary for traditional resistance training to increase muscular strength and mass may be contraindicated for some at risk populations, such as diseased populations and the elderly. Therefore, an alternative exercise modality is required. Recently, blood flow restriction (BFR) with low intensity resistance exercise (LIRE) has been used for such special populations to improve their function and exercise capacity. Although BFR+LIRE has been intensively studied for a decade, a comprehensive review detailing the effects of BFR+LIRE on both skeletal muscle and vascular function is not available. Therefore, the purpose of this review is to discuss previous studies documenting the effects of BFR+LIRE on hormonal and transcriptional factors in muscle hypertrophy and vascular function, including changes in hemodynamics, and endothelial function.

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