DOI QR코드

DOI QR Code

Efficacy of mid-upper arm circumference in identification, follow-up and discharge of malnourished children during nutrition rehabilitation

  • Mogendi, Joseph Birundu (Faculty of Bioscience Engineering, Ghent University) ;
  • De Steur, Hans (Faculty of Bioscience Engineering, Ghent University) ;
  • Gellynck, Xavier (Faculty of Bioscience Engineering, Ghent University) ;
  • Saeed, Hibbah Araba (School of Health and Related Research, University of Sheffield) ;
  • Makokha, Anselimo (Department of Food Science, Technology and Nutrition, Faculty of Agriculture, Jomo Kenyatta University of Agriculture and Technology)
  • Received : 2014.05.13
  • Accepted : 2014.09.16
  • Published : 2015.06.01

Abstract

BACKGROUND/OBJECTIVES: Although it is crucial to identify those children likely to be treated in an appropriate nutrition rehabilitation programme and discharge them at the appropriate time, there is no golden standard for such identification. The current study examined the appropriateness of using Mid-Upper Arm Circumference for the identification, follow-up and discharge of malnourished children. We also assessed its discrepancy with the Weight-for-Height based diagnosis, the rate of recovery, and the discharge criteria of the children during nutrition rehabilitation. SUBJECTS/METHODS: The study present findings from 156 children (aged 6-59 months) attending a supplementary feeding programme at Makadara and Jericho Health Centres, Eastern District of Nairobi, Kenya. Records of age, weight, height and mid-upper arm circumference were selected at three stages of nutrition rehabilitation: admission, follow-up and discharge. The values obtained were then used to calculate z-scores as defined by WHO Anthro while estimating different diagnostic indices. RESULTS: Mid-upper arm circumference single cut-off (< 12.5 cm) was found to exhibit high values of sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio, negative likelihood ratio at both admission and discharge. Besides, children recorded higher rate of recovery at 86 days, an average increment of 0.98 cm at the rate of 0.14mm/day, and a weight gain of 13.49gm/day, albeit higher in female than their male counterparts. Nevertheless, children admitted on basis of low MUAC had a significantly higher MUAC gain than WH at 0.19mm/day and 0.13mm/day respectively. CONCLUSIONS: Mid-upper arm circumference can be an appropriate tool for identifying malnourished children for admission to nutrition rehabilitation programs. Our results confirm the appropriateness of this tool for monitoring recovery trends and discharging the children thereafter. In principle the tool has potential to minimize nutrition rehabilitation costs, particularly in community therapeutic centres in developing countries.

Keywords

References

  1. Blossner M, de Onis M. Malnutrition: Quantifying the Health Impact at National and Local Levels. Geneva: World Health Organization; 2005.
  2. Caulfield LE, de Onis M, Blossner M, Black RE. Undernutrition as an underlying cause of child deaths associated with diarrhea, pneumonia, malaria, and measles. Am J Clin Nutr 2004;80:193-8. https://doi.org/10.1093/ajcn/80.1.193
  3. de Onis M, Blossner M. The World Health Organization Global Database on Child Growth and Malnutrition: methodology and applications. Int J Epidemiol 2003;32:518-26. https://doi.org/10.1093/ije/dyg099
  4. Roberfroid D, Hammami N, Lachat C, Weise Prinzo Z, Sibson V, Guesdon B, Goosens S, Kolsteren P. Utilization of Mid-upper Arm Circumference Versus Weight-for-Height in Nutritional Rehabilitation Programmes: a Systematic Review of Evidence. Geneva: World Health Organization; 2013.
  5. World Health Organization (CH). The World Health Report 2002. Reducing Risks, Promoting Healthy Life. Geneva: World Health Organization; 2002.
  6. Goossens S, Bekele Y, Yun O, Harczi G, Ouannes M, Shepherd S. Mid-upper arm circumference based nutrition programming: evidence for a new approach in regions with high burden of acute malnutrition. PLoS One 2012;7:e49320. https://doi.org/10.1371/journal.pone.0049320
  7. Myatt M, Khara T, Collins S. A review of methods to detect cases of severely malnourished children in the community for their admission into community-based therapeutic care programs. Food Nutr Bull 2006;27:S7-23. https://doi.org/10.1177/15648265060273S302
  8. Black RE, Allen LH, Bhutta ZA, Caulfield LE, de Onis M, Ezzati M, Mathers C, Rivera J; Maternal and Child Undernutrition Study Group. Maternal and child undernutrition: global and regional exposures and health consequences. Lancet 2008;371:243-60. https://doi.org/10.1016/S0140-6736(07)61690-0
  9. Tekeste A, Wondafrash M, Azene G, Deribe K. Cost effectiveness of community-based and in-patient therapeutic feeding programs to treat severe acute malnutrition in Ethiopia. Cost Eff Resour Alloc 2012;10:4. https://doi.org/10.1186/1478-7547-10-4
  10. Collins S. Changing the way we address severe malnutrition during famine. Lancet 2001;358:498-501. https://doi.org/10.1016/S0140-6736(01)05630-6
  11. World Health Organization; World Food Programme; United Nations System Standing Committee on Nutrition; The United Nations Children's Fund. Community-Based Management of Severe Acute Malnutrition [Internet]. Geneva: World Health Organization; 2007 [cited 2014 March 10]. Available from: http://www.unicef.org/ publications/files/Community_Based_Management_of_Sever_Acut e__Malnutirtion.pdf.
  12. Bhutta ZA, Ahmed T, Black RE, Cousens S, Dewey K, Giugliani E, Haider BA, Kirkwood B, Morris SS, Sachdev HP, Shekar M; Maternal and Child Undernutrition Study Group. What works? Interventions for maternal and child undernutrition and survival. Lancet 2008;371:417-40. https://doi.org/10.1016/S0140-6736(07)61693-6
  13. Sadler K. Community-based therapeutic care: treating severe acute malnutrition in sub-Saharan Africa [doctoral thesis]. London: University of London; 2009.
  14. Dale NM, Myatt M, Prudhon C, Briend A. Using mid-upper arm circumference to end treatment of severe acute malnutrition leads to higher weight gains in the most malnourished children. PLoS One 2013;8:e55404. https://doi.org/10.1371/journal.pone.0055404
  15. Shakir A. The surveillance of protein-calorie malnutrition by simple and economical means (a report to UNICEF). J Trop Pediatr Environ Child Health 1975;21:69-85.
  16. Roy NC. Use of mid-upper arm circumference for evaluation of nutritional status of children and for identification of high-risk groups for malnutrition in rural Bangladesh. J Health Popul Nutr 2000;18:171-80.
  17. Bryce J, Coitinho D, Darnton-Hill I, Pelletier D, Pinstrup-Andersen P; Maternal and Child Undernutrition Study Group. Maternal and child undernutrition: effective action at national level. Lancet 2008;371:510-26. https://doi.org/10.1016/S0140-6736(07)61694-8
  18. Briend A, Maire B, Fontaine O, Garenne M. Mid-upper arm circumference and weight-for-height to identify high-risk malnourished under-five children. Matern Child Nutr 2012;8:130-3. https://doi.org/10.1111/j.1740-8709.2011.00340.x
  19. Mwangome MK, Fegan G, Mbunya R, Prentice AM, Berkley JA. Reliability and accuracy of anthropometry performed by community health workers among infants under 6 months in rural Kenya. Trop Med Int Health 2012;17:622-9. https://doi.org/10.1111/j.1365-3156.2012.02959.x
  20. Lapidus N, Minetti A, Djibo A, Guerin PJ, Hustache S, Gaboulaud V, Grais RF. Mortality risk among children admitted in a large-scale nutritional program in Niger, 2006. PLoS One 2009;4:e4313. https://doi.org/10.1371/journal.pone.0004313
  21. Fernandez MA, Delchevalerie P, Van Herp M. Accuracy of MUAC in the detection of severe wasting with the new WHO growth standards. Pediatrics 2010;126:e195-201. https://doi.org/10.1542/peds.2009-2175
  22. Myatt M, Duffield A, Seal A, Pasteur F. The effect of body shape on weight-for-height and mid-upper arm circumference based case definitions of acute malnutrition in Ethiopian children. Ann Hum Biol 2009;36:5-20. https://doi.org/10.1080/03014460802471205
  23. Lagrone L, Cole S, Schondelmeyer A, Maleta K, Manary MJ. Locally produced ready-to-use supplementary food is an effective treatment of moderate acute malnutrition in an operational setting. Ann Trop Paediatr 2010;30:103-8. https://doi.org/10.1179/146532810X12703901870651
  24. Connor NE, Manary MJ, Maleta K. Monitoring the adequacy of catch-up growth among moderately malnourished children receiving home-based therapy using mid-upper arm circumference in southern Malawi. Matern Child Health J 2011;15:980-4. https://doi.org/10.1007/s10995-010-0569-8
  25. Ciliberto MA, Sandige H, Ndekha MJ, Ashorn P, Briend A, Ciliberto HM, Manary MJ. Comparison of home-based therapy with readyto-use therapeutic food with standard therapy in the treatment of malnourished Malawian children: a controlled, clinical effectiveness trial. Am J Clin Nutr 2005;81:864-70. https://doi.org/10.1093/ajcn/81.4.864
  26. Smith LC, Haddad L. Explaining Child Malnutrition in Developing Countries: a Cross-Country Analysis. Washington, D.C.: International Food Policy Research Institute; 2000.
  27. Lauritsen JM, Bruus M. EpiData (version 3): a Comprehensive Tool for Validated Entry and Documentation of Data. Odense: The EpiData Association; 2008.
  28. StataCorp. Stata: Release 12. Statistical Software. College Station (TX): StataCorp LP.; 2011.
  29. Hop le T, Gross R, Sastroamidjojo S, Giay T, Schultink W. Midupper-arm circumference development and its validity in assessment of undernutrition. Asia Pac J Clin Nutr 1998;7:65-9.
  30. Pelletier DL. The potentiating effects of malnutrition on child mortality: epidemiologic evidence and policy implications. Nutr Rev 1994;52:409-15.
  31. Singh AS, Kang G, Ramachandran A, Sarkar R, Peter P, Bose A. Locally made ready to use therapeutic food for treatment of malnutrition a randomized controlled trial. Indian Pediatr 2010;47:679-86. https://doi.org/10.1007/s13312-010-0100-8

Cited by

  1. Malnourishment and length of hospital stay among paediatric cancer patients with febrile neutropaenia: a developing country perspective vol.6, pp.3, 2016, https://doi.org/10.1136/bmjspcare-2015-001020
  2. Mothers screening for malnutrition by mid-upper arm circumference is non-inferior to community health workers: results from a large-scale pragmatic trial in rural Niger vol.74, pp.1, 2016, https://doi.org/10.1186/s13690-016-0149-5
  3. Comparing performance of mothers using simplified mid-upper arm circumference (MUAC) classification devices with an improved MUAC insertion tape in Isiolo County, Kenya vol.76, pp.1, 2018, https://doi.org/10.1186/s13690-018-0260-x
  4. How healthy are children one year after discharge from nutritional rehabilitation centres? pp.1758-1133, 2018, https://doi.org/10.1177/0049475518786854
  5. Identifying acute malnutrition - do we have an answer for policy makers? vol.2, pp.None, 2016, https://doi.org/10.1186/s40795-016-0060-z
  6. Valuing increased zinc (Zn) fertiliser-use in Pakistan vol.411, pp.1, 2015, https://doi.org/10.1007/s11104-016-2961-7
  7. Mid-upper arm circumference (MUAC) performance versus weight for height in South African children (0-59 months) with acute malnutrition vol.30, pp.2, 2015, https://doi.org/10.1080/16070658.2016.1255483
  8. Contribution of Different Anthropometric Measures to BMI towards Assessing Overweight and Obesity of (6-10Year) Children in Kolkata, India vol.9, pp.2, 2017, https://doi.org/10.1080/09751270.2017.1421124
  9. Comparison of Weight-for-Height Z-score and Mid-Upper Arm Circumference to Diagnose Moderate and Severe Acute Malnutrition in children aged 6-59 months vol.35, pp.2, 2015, https://doi.org/10.12669/pjms.35.2.45
  10. The relationship between wasting and stunting in Cambodian children: Secondary analysis of longitudinal data of children below 24 months of age followed up until the age of 59 months vol.16, pp.11, 2015, https://doi.org/10.1371/journal.pone.0259765