Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Comparative Study between the Allostasis Load and Chiljeongsang

알로스테시스 과부하와 칠정상에 관한 비교 고찰

  • Joung, Jin Yong (Liver & Immunology Research Center, Daejeon Korean Hospital of Daejeon University) ;
  • Kim, Jun Young (Liver & Immunology Research Center, Daejeon Korean Hospital of Daejeon University) ;
  • Cho, Jung Hyo (Liver & Immunology Research Center, Daejeon Korean Hospital of Daejeon University) ;
  • Son, Chang Gue (Liver & Immunology Research Center, Daejeon Korean Hospital of Daejeon University)
  • 정진용 (대전대학교 대전한방병원) ;
  • 김준영 (대전대학교 대전한방병원) ;
  • 조정효 (대전대학교 대전한방병원) ;
  • 손창규 (대전대학교 대전한방병원)
  • Received : 2016.09.20
  • Accepted : 2016.11.04
  • Published : 2016.12.25
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Abstract

If human body is exposed to the continuous stress, it becomes allostasis load which is the condition of homeostasis broken. Its evolutional ecologic point of view and the relation with chiljeongsnag which is a theory in Oriental Medicine were investigated. Upon evolutional ecologic point of view by Maynard Smith, people can be divided by Hawks and Doves resulting in different types of allostasis in response of the stress. Hawks people who are active and aggressive get easily anger in the stressful situation to be vulnerable to the inflammatory hepatic diseases by enhancing Th1 immune system. On the other hand, Doves people who are passive and calm get easily depressed with sadness in the stressful situation to be vulnerable to the allergic pulmonary diseases by enhancing Th2 immune system. According to constitution theory of Oriental Medicine, Yangin and Eumin show the different features of responses to the stress generating Chiljeongsang. With excessive stress continuously, Yangin consider the feeling of anger mainly resulting in Qi reversal and liver damage, while Eumin consider the feeling of sadness mainly in consumption of Qi and lung damage. Hawks and Yangin, and Doves and Eumin show the common behaviors in response to the stress demonstrating the similar features including allostasis load and Chiljeongsang. In the clinical practices with the stressful patients, the viewpoint to consider the behaviors and feelings of the subjects to receive the stress simultaneously can be the new approaching method in Psychosomatic Medicine.

Keywords

References

  1. McEwen, B.S. Stress, adaptation, and disease. Allostasis and allostatic load. Ann N Y Acad Sci. 840: 33-44, 1988.
  2. Heo, J. Donguibogam. Seoul. Bubinmunhwasa. p 323, 555, 2005.
  3. Kaplan, M.H., Wheeler, W.F. Stress and diseases of the upper gut. I. Stress and liver disease. Mt Sinai J Med. 50(3):225-227, 1983.
  4. Chida, Y., Sudo, N., Kubo, C. Does stress exacerbate liver diseases? J Gastroenterol Hepatol. 21(1 Pt 2):202-208, 2006. https://doi.org/10.1111/j.1440-1746.2006.04110.x
  5. Haczku, A., Panettieri, R.A. Social stress and asthma: The role of corticosteroid insensitivity. J Allergy Clin Immunol. 125(3):550-558, 2010. https://doi.org/10.1016/j.jaci.2009.11.005
  6. Maynard Smith J. Evolution and the Theory of Games. Cambridge: Cambridge University Press. 1982.
  7. Korte, S.M., Koolhaas, J.M., Wingfield, J.C., McEwen, B.S. The Darwinian concept of stress: benefits of allostasis and costs of allostatic load and the trade-offs in health and disease. Neuroscience & Biobehavioral Reviews. 29(1):3-38, 2005. https://doi.org/10.1016/j.neubiorev.2004.08.009
  8. Verbeek, M.E.M., Goede, P.D., Drent, P.J., Wiepkema, P.R. Individual Behavioural Characteristics and Dominance in Aviary Groups of Great Tits. Behaviour. 136(1):23-48, 1999. https://doi.org/10.1163/156853999500659
  9. de Boer, S.F., van der Vegt, B.J., Koolhaas, J.M. Individual variation in aggression of feral rodent strains: a standard for the genetics of aggression and violence? Behav Genet. 33(5):485-501, 2003. https://doi.org/10.1023/A:1025766415159
  10. Veenema, A.H., Meijer, O.C., de Kloet, E.R., Koolhaas, J.M. Genetic selection for coping style predicts stressor susceptibility. J Neuroendocrinol. 15(3):256-267, 2003. https://doi.org/10.1046/j.1365-2826.2003.00986.x
  11. van Oortmerssen, G.A., Busser, J. Studies in wild house mice 3 disruptive selection on aggression as a possible force in evolution. In: Brain PF, Mainardi D, Parmigiani S. House mouse aggression: a model for understanding the evolution of social behavior. New York, Harwood Academic Publishers. pp 87-117, 1989.
  12. Sin, M.K., Hong, M.C., Ryu, D.G., Kwon, G.B., Kim, G.J., Kwon, Y.G., Shin, H.M., Kang, J.S., Kim, B.S., Lee, Y.T., Kang, K.H., Kim, M.D., Lee, S.J., Yu, Y.J., Lee, C.Y., Park, W.Y., Jang, G.S., Choi, C.H., Kim, H.H., Chae, H. The textbook of korean medical physiology. Gyeonggi-Do Paju. Jipmundang. p 489, 2008.
  13. Kang, C.M., Kang, J.S., Kim, B.S. Analysis of Differential Diagnosis System in Sasang Typology on the Basis of Greater-Lesser-Yin-Yang and Eight Principle Pattern Identification. Korean J. Oriental Physiology & Pathology. 22(5):1125-1131, 2008.
  14. Choi, H.C. An Application of Sasangchejil(A Theory of Four Different Types of Persons) to the Study of Patterns of Media Use. Journal of Communication Research. 47(1):170-203, 2010. https://doi.org/10.22174/jcr.2010.47.1.170
  15. Chae, H., Lyoo, I.K., Lee, S.J., Cho, S., Bae, H., Hong, M., Shin, M. An alternative way to individualized medicine: psychological and physical traits of Sasang typology. J Altern Complement Med. 9(4):519-528, 2003. https://doi.org/10.1089/107555303322284811
  16. Jung, S.A., Kim, S.H., Yoo, J.S., Lee, S.G. Study about the Psychological Factors of Sasang Constitution Classified by QSCC II. J of Oriental Neuropsychiatry. 23(1):83-92, 2012. https://doi.org/10.7231/JON.2012.23.1.083
  17. Kim, M.H. Menopausal Symptoms according to Sasang Constitution and Menopausal Status among Perimenopause Women. Korean J Women Health Nurs. 18(1):28-37, 2012. https://doi.org/10.4069/kjwhn.2012.18.1.28
  18. Kim, B.S., Cho, K.R., Bae, H.S. A Study on the Effects of Psychological Traits (Depression, Anxiety, Anger) of the Middle and Old Aged. Journal for the Buddhist Studies. 67: 187-211, 2014.
  19. McEwen, B.S., Wingfield, J.C. The concept of allostasis in biology and biomedicine. Horm Behav. 43(1):2-15, 2003. https://doi.org/10.1016/S0018-506X(02)00024-7
  20. Korte, S.M., Buwalda, B., Bouws, G.A., Koolhaas, J.M., Maes, F.W., Bohus, B. Conditioned neuroendocrine and cardiovascular stress responsiveness accompanying behavioral passivity and activity in aged and in young rats. Physiol Behav. 51(4):815-822, 1992. https://doi.org/10.1016/0031-9384(92)90120-Q
  21. Korte, S.M., de Boer, S.F., de Kloet, E.R., Bohus, B. Anxiolytic-like effects of selective mineralocorticoid and glucocorticoid antagonists on fear-enhanced behavior in the elevated plus-maze. Psychoneuroendocrinology. 20(4):385-394, 1995. https://doi.org/10.1016/0306-4530(94)00069-7
  22. Buwalda, B., Koolhaas, J.M., Bohus, B. Behavioral and cardiac responses to mild stress in young and aged rats: effects of amphetamine and vasopressin. Physiol Behav. 51(2):211-216, 1992. https://doi.org/10.1016/0031-9384(92)90133-M
  23. Elenkov, I.J. Glucocorticoids and the Th1/Th2 balance. Ann N Y Acad Sci. 1024: 138-146, 2004. https://doi.org/10.1196/annals.1321.010
  24. Dhabhar, F.S., Miller, A.H., McEwen, B.S., Spencer, R.L. Effects of stress on immune cell distribution. Dynamics and hormonal mechanisms. J Immunol. 154(10):5511-5527, 1995.
  25. Jin, J.P. Hwangjenegyung doksongbon. Seoul. Bubinmunhwasa. pp 230-231, 2009.
  26. Yoon, E.K., Baik, Y.S., Jeong, C.H. Emotional factors in the mechanism of Chiljeongsang. Journal of Korean Medical classics. 24(4):48-51, 2011.
  27. Gao, B., Jeong, W.I., Tian, Z. Liver: An organ with predominant innate immunity. Hepatology. 47(2):729-736, 2008. https://doi.org/10.1002/hep.22034
  28. Knolle, P.A., Gerken, G. Local control of the immune response in the liver. Immunological Reviews. 174(1):21-34, 2000. https://doi.org/10.1034/j.1600-0528.2002.017408.x
  29. Cripps, J.G., Celaj, S., Burdick, M., Strieter, R.M., Gorham, J.D. Liver inflammation in a mouse model of Th1 hepatitis despite the absence of invariant NKT cells or the Th1 chemokine receptors CXCR3 and CCR5. Lab Invest. 92(10):1461-1471, 2012. https://doi.org/10.1038/labinvest.2012.104
  30. Blackmore, L.J., Ryan, J.M., Huang, X., Hussain, M., Triantafyllou, E., Vergis, N., Vijay, G.M., Antoniades, C.G., Thursz, M.R., Jassem, W., Vergani, D., Shawcross, D.L., Ma, Y. Acute alcoholic hepatitis and cellular Th1 immune responses to alcohol dehydrogenase. The Lancet. 26: 385, 2015.
  31. Murdoch, J.R., Lloyd, C.M. Chronic inflammation and asthma. Mutat Res. 690(1-2):24-39, 2010. https://doi.org/10.1016/j.mrfmmm.2009.09.005
  32. Lee, G.E., Lyu, Y.S., Kang, H.W. Study of Pathologic Mechanism Related Chiljeong-Based on a Literature Review of Donguibogam. J of Oriental Neuropsychiatry. 25(1):85-108, 2014. https://doi.org/10.7231/jon.2014.25.1.085
  33. Curiati, J.A., Bocchi, E., Freire, J.O., et al. Meditation Reduces Sympathetic Activation and Improves the Quality of Life in Elderly Patients with Optimally Treated Heart Failure: A Prospective Randomized Study. The Journal of Alternative and Complementary Medicine. 11(3):465-472, 2005. https://doi.org/10.1089/acm.2005.11.465
  34. Hill, E.E., Zack, E., Battaglini, C., Viru, M., Viru, A., Hackney, A.C. Exercise and circulating Cortisol levels: The intensity threshold effect. J Endocrinol Invest. 31(7):587-591, 2014. https://doi.org/10.1007/BF03345606
  35. Sin, M.K., Hong, M.C., Ryu, D.G., Kwon, G.B., Kim, G.J., Kwon, Y.G., Shin, H.M., Kang, J.S., Kim, B.S., Lee, Y.T., Kang, K.H., Kim, M.D., Lee, S.J., Yu, Y.J., Lee, C.Y., Park, W.Y., Jang, G.S., Choi, C.H., Kim, H.H., Chae, H. The textbook of korean medical physiology. Gyeonggido Paju. Jipmundang. p 478, 2008.